Effect of BRCA Mutations on Metastatic Relapse and Cause-specific Survival After Radical Treatment for Localised Prostate Cancer.-论文-万方医学网

第一作者： Elena,Castro

第一单位： Prostate Cancer Unit, Clinical Research Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain; Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, UK. Electronic address: ecastro@cnio.es.

作者： Elena,Castro ^[1] ; Chee,Goh ^[2] ; Daniel,Leongamornlert ^[2] ; Ed,Saunders ^[2] ; Malgorzata,Tymrakiewicz ^[2] ; Tokhir,Dadaev ^[2] ; Koveela,Govindasami ^[2] ; Michelle,Guy ^[2] ; Steve,Ellis ^[3] ; Debra,Frost ^[3] ; Elizabeth,Bancroft ^[2] ; Trevor,Cole ^[4] ; Marc,Tischkowitz ^[5] ; M John,Kennedy ^[6] ; Jacqueline,Eason ^[7] ; Carole,Brewer ^[8] ; D Gareth,Evans ^[9] ; Rosemarie,Davidson ^[10] ; Diana,Eccles ^[11] ; Mary E,Porteous ^[12] ; Fiona,Douglas ^[13] ; Julian,Adlard ^[14] ; Alan,Donaldson ^[15] ; Antonis C,Antoniou ^[3] ; Zsofia,Kote-Jarai ^[2] ; Douglas F,Easton ^[3] ; David,Olmos ^[16] ; Rosalind,Eeles ^[2]

作者单位： Prostate Cancer Unit, Clinical Research Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain; Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, UK. Electronic address: ecastro@cnio.es. ^[1] Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, UK. ^[2] Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. ^[3] West Midlands Regional Genetics Service, Birmingham Women's Hospital Healthcare NHS Trust, Edgbaston, Birmingham, UK. ^[4] Department of Medical Genetics, University of Cambridge, Cambridge, UK. ^[5] Academic Unit of Clinical and Molecular Oncology, Trinity College Dublin and St. James's Hospital, Dublin, Ireland. ^[6] Nottingham Clinical Genetics Service, Nottingham University Hospitals NHS Trust, Nottingham, UK. ^[7] Department of Clinical Genetics, Royal Devon and Exeter Hospital, Exeter, UK. ^[8] Genetic Medicine, Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK. ^[9] Ferguson-Smith Centre for Clinical Genetics, Yorkhill Hospitals, Glasgow, UK. ^[10] University of Southampton Faculty of Medicine, Southampton University Hospitals NHS Trust, Southampton, UK. ^[11] South East of Scotland Regional Genetics Service, Western General Hospital, Edinburgh, UK. ^[12] Institute of Genetic Medicine, Centre for Life, Newcastle Upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, UK. ^[13] Yorkshire Regional Genetics Service, Leeds, UK. ^[14] Clinical Genetics Department, St. Michael's Hospital, Bristol, UK. ^[15] Prostate Cancer Unit, Clinical Research Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain. Electronic address: dolmos@cnio.es. ^[16]

医学主题词 BRCA1蛋白质(BRCA1 Protein);BRCA2蛋白质(BRCA2 Protein);DNA突变分析(DNA Mutational Analysis);无病生存(Disease-Free Survival);疾病遗传易感性(Genetic Predisposition to Disease);生殖细胞系突变(Germ-Line Mutation);人类(Humans);激肽释放酶类(Kallikreins);Kaplan-Meiers评估(Kaplan-Meier Estimate);男(雄)性(Male);中年人(Middle Aged);多元分析(Multivariate Analysis);肿瘤转移(Neoplasm Metastasis);表型(Phenotype);比例危险度模型(Proportional Hazards Models);前列腺特异抗原(Prostate-Specific Antigen);前列腺切除术(Prostatectomy);前列腺肿瘤(Prostatic Neoplasms);回顾性研究(Retrospective Studies);危险性评估(Risk Assessment);危险因素(Risk Factors);时间因素(Time Factors);治疗结果(Treatment Outcome)

DOI 10.1016/j.eururo.2014.10.022

PMID 25454609

发布时间 2025-05-29

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Effect of BRCA Mutations on Metastatic Relapse and Cause-specific Survival After Radical Treatment for Localised Prostate Cancer.

European urology

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European urology

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Effect of BRCA Mutations on Metastatic Relapse and Cause-specific Survival After Radical Treatment for Localised Prostate Cancer.

European urology

相似文献

同项目论文

European urology

相关期刊

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