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Pharmacokinetics and tolerability of oral sildenafil in adults with cystic fibrosis lung disease.

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第一作者： J L,Taylor-Cousar

第一单位： Department of Medicine, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, United States; Department of Pediatrics, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, United States. Electronic address: Taylor-CousarJ@NJHealth.org.

作者： J L,Taylor-Cousar ^[1] ; C,Wiley ^[2] ; L A,Felton ^[2] ; C,St Clair ^[3] ; M,Jones ^[3] ; D,Curran-Everett ^[4] ; K,Poch ^[3] ; D P,Nichols ^[5] ; G M,Solomon ^[6] ; M T,Saavedra ^[3] ; F J,Accurso ^[7] ; J A,Nick ^[3]

作者单位： Department of Medicine, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, United States; Department of Pediatrics, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, United States. Electronic address: Taylor-CousarJ@NJHealth.org. ^[1] Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico, Albuquerque, NM, United States. ^[2] Department of Medicine, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, United States. ^[3] Division of Biostatistics and Bioinformatics, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, United States; Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Denver, Denver, CO 80262, United States. ^[4] Department of Medicine, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, United States; Department of Pediatrics, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, United States. ^[5] Internal Medicine, University of Alabama, 1720 2nd Ave South, Birmingham, AL 35294, United States. ^[6] Department of Pediatrics, University of Colorado School of Medicine, Children's Hospital Colorado, 13123 E 16th Ave, Aurora, CO 80045, United States. ^[7]

关键词 Biomarkers Cystic fibrosis Inflammation Pharmacokinetics Phosphodiesterase inhibitors Sildenafil