Ida-1, the Caenorhabditis elegans orthologue of mammalian diabetes autoantigen IA-2, potentially acts as a common modulator between Parkinson's disease and Diabetes: role of Daf-2/Daf-16 insulin like signalling pathway.

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作者： Soobiya,Fatima ^[1] ; Rizwanul,Haque ^[1] ; Pooja,Jadiya ^[1] ; Shamsuzzama ^[1] ; Lalit,Kumar ^[1] ; Aamir,Nazir ^[1]

作者单位： Laboratory of Functional Genomics and Molecular Toxicology, Division of Toxicology, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India. ^[1]

主题词动物(Animals);动物, 基因修饰(Animals, Genetically Modified);秀丽新小杆线虫(Caenorhabditis elegans);漂亮新小杆线虫蛋白质类(Caenorhabditis elegans Proteins);细胞核(Cell Nucleus);糖尿病(Diabetes Mellitus);叉头转录因子类(Forkhead Transcription Factors);基因表达(Gene Expression);绿色荧光蛋白质类(Green Fluorescent Proteins);人类(Humans);膜糖蛋白类(Membrane Glycoproteins);显微镜检查, 荧光(Microscopy, Fluorescence);运动活动(Motor Activity);帕金森病(Parkinson Disease);蛋白质酪氨酸磷酸酶类(Protein Tyrosine Phosphatases);RNA干扰(RNA Interference);受体, 胰岛素(Receptor, Insulin);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);信号传导(Signal Transduction);α突触核蛋白(alpha-Synuclein)

DOI 10.1371/journal.pone.0113986

PMID 25469508

发布时间 2018-11-13

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2014年9卷12期

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Ida-1, the Caenorhabditis elegans orthologue of mammalian diabetes autoantigen IA-2, potentially acts as a common modulator between Parkinson's disease and Diabetes: role of Daf-2/Daf-16 insulin like signalling pathway.

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Ida-1, the Caenorhabditis elegans orthologue of mammalian diabetes autoantigen IA-2, potentially acts as a common modulator between Parkinson's disease and Diabetes: role of Daf-2/Daf-16 insulin like signalling pathway.

PloS one

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