Pioglitazone inhibits advanced glycation end product-induced TNF-α and MMP-13 expression via the antagonism of NF-κB activation in chondrocytes.
第一作者:
Cheng,Chen
第一单位:
Department of Orthopedics, The 163rd Central Hospital of the People's Liberation Army, The Second Affiliated Hospital of Hunan Normal University, Changsha, PR China.
作者:
主题词
动物(Animals);细胞, 培养的(Cells, Cultured);软骨细胞(Chondrocytes);降血糖药(Hypoglycemic Agents);男(雄)性(Male);基质金属蛋白酶13(Matrix Metalloproteinase 13);PPARγ(PPAR gamma);RNA, 信使(RNA, Messenger);兔(Rabbits);噻唑烷二酮类(Thiazolidinediones);转录因子RelA(Transcription Factor RelA);肿瘤坏死因子α(Tumor Necrosis Factor-alpha)
DOI
10.1159/000369074
PMID
25471680
发布时间
2018-12-02
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Pharmacology
265-72页
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