Norepinephrine promotes tumor microenvironment reactivity through β3-adrenoreceptors during melanoma progression.

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作者： Maura,Calvani ^[1] ; Floriane,Pelon ^[1] ; Giuseppina,Comito ^[1] ; Maria Letizia,Taddei ^[1] ; Silvia,Moretti ^[2] ; Stefania,Innocenti ^[3] ; Romina,Nassini ^[4] ; Gianni,Gerlini ^[5] ; Lorenzo,Borgognoni ^[5] ; Franco,Bambi ^[6] ; Elisa,Giannoni ^[1] ; Luca,Filippi ^[7] ; Paola,Chiarugi ^[1]

作者单位： Department of Experimental and Clinical Biomedical Sciences, University of Florence, Tuscany Tumor Institute and "Center for Research, Transfer and High Education DenoTHE", Florence, Italy. ^[1] Department of Surgery and Translational Medicine, Dermatology Section University of Florence, Florence, Italy. ^[2] Division of Pathology, Pistoia Hospital, Pistoia, Italy. ^[3] Department of Health Sciences, Clinical Pharmacology and Oncology Unit, University of Florence, Florence, Italy. ^[4] Plastic Surgery Unit, Regional Melanoma Referral Center, Tuscan Tumor Institute, Santa Maria Annunziata Hospital, Florence, Italy. ^[5] Transfusion Medicine and Cell Therapy, "A. Meyer" University Children's Hospital, Florence, Italy. ^[6] Neonatal Intensive Care Unit, Medical Surgical Fetal-Neonatal Department, "A. Meyer" University Children's Hospital, Florence, Italy. ^[7]

关键词 cancer-associated fibroblasts macrophages melanoma mesenchymal stem cells tumor microenvironment β-adrenergic receptors