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Exposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegans.

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第一作者： Claudia P,González-Hunt

第一单位： Nicholas School of the Environment, Duke University, Durham, North Carolina, United States of America.

作者： Claudia P,González-Hunt ^[1] ; Maxwell C K,Leung ^[1] ; Rakesh K,Bodhicharla ^[1] ; Madeline G,McKeever ^[1] ; Andrew E,Arrant ^[2] ; Kathleen M,Margillo ^[1] ; Ian T,Ryde ^[1] ; Derek D,Cyr ^[3] ; Sara G,Kosmaczewski ^[4] ; Marc,Hammarlund ^[4] ; Joel N,Meyer ^[1]

作者单位： Nicholas School of the Environment, Duke University, Durham, North Carolina, United States of America. ^[1] Department of Pharmacology and Cancer Biology, Duke University, Durham, North Carolina, United States of America. ^[2] Center for Applied Genomics and Technology, Duke University, Durham, North Carolina, United States of America. ^[3] Department of Genetics, Program in Cellular Neuroscience, Neurodegeneration, and Repair, Yale University School of Medicine, New Haven, Connecticut, United States of America. ^[4]

医学主题词肾上腺素能药(Adrenergic Agents);动物(Animals);秀丽新小杆线虫(Caenorhabditis elegans);DNA损伤(DNA Damage);DNA, 线粒体(DNA, Mitochondrial);多巴胺(Dopamine);多巴胺药(Dopamine Agents);线粒体(Mitochondria);诱变剂(Mutagens);神经变性(Nerve Degeneration);羟多巴胺(Oxidopamine);百草枯(Paraquat)

DOI 10.1371/journal.pone.0114459

PMID 25486066

发布时间 2022-02-23

基金项目

T32 GM007223/GM/NIGMS NIH HHS/United States P40 OD010440/OD/NIH HHS/United States R01-ES017540-01A2/ES/NIEHS NIH HHS/United States R21 NS065468/NS/NINDS NIH HHS/United States R01 ES017540/ES/NIEHS NIH HHS/United States

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