换一批
换一批The cyclin D1-CDK4 oncogenic interactome enables identification of potential novel oncogenes and clinical prognosis.
作者：
关键词
ACN, acetonitrileAES, aggregate expression scoreATCC, American type culture collectionCDK4DMEM, Dulbecco's Modified Eagle's mediumFBS, fetal bovine serumLC-MS/MS, liquid chromatography-tandem mass spectrometryPPI, protein-protein interactionRPMI, Roswell Park Memorial Institute mediumSCNA, somatic copy-number variationTCGA, the cancer genome atlasWB, immunoblottingbreast cancercyclin D1interactomeoncogenesoncogenic signaturesiFKBP4, FKBP4-specific small interfering RNAsiFKBP5, FKBP5-specific small interfering RNAsiRNA, small interfering RNAsicont, control small interfering RNAsicyclin D1, cyclin D1-specific small interfering RNA
主题词
动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);细胞周期蛋白D1(Cyclin D1);细胞周期蛋白依赖激酶4(Cyclin-Dependent Kinase 4);DNA拷贝数变异(DNA Copy Number Variations);女(雌)性(Female);基因表达谱(Gene Expression Profiling);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);小鼠, 裸(Mice, Nude);微丝蛋白质类(Microfilament Proteins);癌基因(Oncogenes);预后(Prognosis);蛋白质结合(Protein Binding);受体, 雌激素(Receptors, Estrogen);存活率分析(Survival Analysis);他克莫司结合蛋白质类(Tacrolimus Binding Proteins)
DOI
10.4161/15384101.2014.946850
PMID
25486477
发布时间
2021-01-29
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Cell cycle (Georgetown, Tex.)
2889-900页
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