Antitumor platinum(II) complexes of N-cyclobutyl-1R,2R-diaminocyclohexane with dicarboxylates as leaving groups.

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作者： Gang,Xu ^[1] ; Jian,Zhao ^[2] ; Shaohua,Gou ^[3] ; Jie,Pang ^[4]

作者单位： Pharmaceutical Research Center, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, Jiangsu, China; Jiangsu Province Hi-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing 211189, Jiangsu, China; State Key Laboratory of Analytical Chemistry for Life Science, Nanjing University, Nanjing 210093, Jiangsu, China. ^[1] Pharmaceutical Research Center, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, Jiangsu, China; Jiangsu Province Hi-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing 211189, Jiangsu, China. ^[2] Pharmaceutical Research Center, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, Jiangsu, China; Jiangsu Province Hi-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing 211189, Jiangsu, China. Electronic address: sgou@seu.edu.cn. ^[3] State Key Laboratory of Analytical Chemistry for Life Science, Nanjing University, Nanjing 210093, Jiangsu, China. ^[4]

关键词 Anticancer platinum(II) complexes Cytotoxicity DNA cleavage N-Cyclobutyl-1R,2R-diaminocyclohexane