Detection of hepatocellular carcinoma in transgenic mice by Gd-DTPA- and rhodamine 123-conjugated human serum albumin nanoparticles in T1 magnetic resonance imaging.-论文-万方医学网

作者： Waralee,Watcharin ^[1] ; Christian,Schmithals ^[2] ; Thomas,Pleli ^[2] ; Verena,Köberle ^[2] ; Hüdayi,Korkusuz ^[3] ; Frank,Hübner ^[4] ; Oliver,Waidmann ^[2] ; Stefan,Zeuzem ^[2] ; Horst-Werner,Korf ^[5] ; Andreas,Terfort ^[6] ; Svetlana,Gelperina ^[7] ; Thomas J,Vogl ^[4] ; Jörg,Kreuter ^[1] ; Albrecht,Piiper ^[8]

作者单位： Institute for Pharmaceutical Technology, Goethe-University of Frankfurt, Max-von-Laue-Straße 7, D-60438 Frankfurt, Germany. ^[1] Department of Medicine 1, University Hospital of Frankfurt, Theodor-Stern-Kai 7, D-60590 Frankfurt, Germany. ^[2] Department of Nuclear Medicine, University Hospital of Frankfurt, Theodor-Stern-Kai 7, D-60590 Frankfurt, Germany. ^[3] Department of Diagnostic and Interventional Radiology, University Hospital of Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany. ^[4] Institute of Anatomy 2, University Hospital of Frankfurt, Theodor-Stern-Kai 7, D-60590 Frankfurt, Germany. ^[5] Institute for Inorganic and Analytic Chemistry, Goethe-University of Frankfurt, Max-von-Laue-Straße 7, D-60438 Frankfurt, Germany. ^[6] Nanosystem Ltd., 115193 Moscow, Russia. ^[7] Department of Medicine 1, University Hospital of Frankfurt, Theodor-Stern-Kai 7, D-60590 Frankfurt, Germany. Electronic address: piiper@med.uni-frankfurt.de. ^[8]

主题词动物(Animals);癌, 肝细胞(Carcinoma, Hepatocellular);细胞存活(Cell Survival);造影剂(Contrast Media);乙二胺类(Ethylenediamines);辅药(Excipients);钆DTPA(Gadolinium DTPA);基因, myc(Genes, myc);人类(Humans);肝(Liver);肝肿瘤(Liver Neoplasms);巨噬细胞, 腹膜(Macrophages, Peritoneal);磁共振成像(Magnetic Resonance Imaging);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);纳米粒子(Nanoparticles);粒子大小(Particle Size);聚乙烯二醇类(Polyethylene Glycols);若丹明123(Rhodamine 123);血清白蛋白(Serum Albumin);组织分布(Tissue Distribution);转化生长因子α(Transforming Growth Factor alpha)

DOI 10.1016/j.jconrel.2014.11.023

PMID 25499552

发布时间 2018-12-02

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Detection of hepatocellular carcinoma in transgenic mice by Gd-DTPA- and rhodamine 123-conjugated human serum albumin nanoparticles in T1 magnetic resonance imaging.

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Detection of hepatocellular carcinoma in transgenic mice by Gd-DTPA- and rhodamine 123-conjugated human serum albumin nanoparticles in T1 magnetic resonance imaging.

Journal of controlled release

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Journal of controlled release

相关期刊

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