Diminished transmission of drug resistant HIV-1 variants with reduced replication capacity in a human transmission model.

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作者： Marieke,Pingen ^[1] ; Ramin,Sarrami-Forooshani ^[2] ; Annemarie M J,Wensing ^[3] ; Petra,van Ham ^[4] ; Agata,Drewniak ^[5] ; Charles A B,Boucher ^[6] ; Teunis B H,Geijtenbeek ^[7] ; Monique,Nijhuis ^[8]

作者单位： Virology, Department of Medical Microbiology, University Medical Center Utrecht, Heidelberglaan 100, 3584CX, Utrecht, the Netherlands. marieke_pingen@hotmail.com. ^[1] Department of Virology, Erasmus Medical Center, Rotterdam, the Netherlands. marieke_pingen@hotmail.com. ^[2] Department of Experimental Immunology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, the Netherlands. r.sarrami@amc.uva.nl. ^[3] Virology, Department of Medical Microbiology, University Medical Center Utrecht, Heidelberglaan 100, 3584CX, Utrecht, the Netherlands. a.m.j.wensing@umcutrecht.nl. ^[4] Virology, Department of Medical Microbiology, University Medical Center Utrecht, Heidelberglaan 100, 3584CX, Utrecht, the Netherlands. p.m.vanham@umcutrecht.nl. ^[5] Department of Experimental Immunology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, the Netherlands. a.a.drewniak@amc.uva.nl. ^[6] Department of Virology, Erasmus Medical Center, Rotterdam, the Netherlands. c.boucher@erasmusmc.nl. ^[7] Department of Experimental Immunology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, the Netherlands. t.b.geijtenbeek@amc.uva.nl. ^[8] Virology, Department of Medical Microbiology, University Medical Center Utrecht, Heidelberglaan 100, 3584CX, Utrecht, the Netherlands. m.nijhuis@umcutrecht.nl. ^[9]

主题词细胞, 培养的(Cells, Cultured);树突细胞(Dendritic Cells);抗药性, 病毒(Drug Resistance, Viral);HIV逆转录酶(HIV Reverse Transcriptase);HIV-1(HIV-1);人类(Humans);突变蛋白质类(Mutant Proteins);突变, 误义(Mutation, Missense);毒力(Virulence);病毒复制(Virus Replication)

DOI 10.1186/s12977-014-0113-9

PMID 25499671

发布时间 2018-11-13

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Retrovirology

2014年11卷

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Diminished transmission of drug resistant HIV-1 variants with reduced replication capacity in a human transmission model.

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Diminished transmission of drug resistant HIV-1 variants with reduced replication capacity in a human transmission model.

Retrovirology

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Retrovirology

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