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首页> The Journal of biological chemistry> Topological analysis of Hedgehog acyltransferase, a multipalmitoylated transmembrane protein.

Topological analysis of Hedgehog acyltransferase, a multipalmitoylated transmembrane protein.

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作者： Antonio D,Konitsiotis ^[1] ; Biljana,Jovanović ^[1] ; Paulina,Ciepla ^[2] ; Martin,Spitaler ^[3] ; Thomas,Lanyon-Hogg ^[4] ; Edward W,Tate ^[5] ; Anthony I,Magee ^[6]

作者单位： From the Molecular Medicine Section and. ^[1] Department of Chemistry, and Institute of Chemical Biology Imperial College London, Sir Alexander Fleming Building, South Kensington, London SW7 2AZ, United Kingdom. ^[2] FILM (Facility for Imaging by Light Microscopy), National Heart and Lung Institute. ^[3] Department of Chemistry, and. ^[4] Department of Chemistry, and Institute of Chemical Biology Imperial College London, Sir Alexander Fleming Building, South Kensington, London SW7 2AZ, United Kingdom e.tate@imperial.ac.uk. ^[5] From the Molecular Medicine Section and Institute of Chemical Biology Imperial College London, Sir Alexander Fleming Building, South Kensington, London SW7 2AZ, United Kingdom t.magee@imperial.ac.uk. ^[6]

关键词 Acyltransferase Cancer Click Chemistry HHAT Hedgehog Signaling Pathway MBOAT Protein Palmitoylation Topology Transmembrane Domain

主题词酰基转移酶类(Acyltransferases);氨基酸特征结构(Amino Acid Motifs);催化域(Catalytic Domain);HEK293细胞(HEK293 Cells);人类(Humans);脂化作用(Lipoylation);突变(Mutation);蛋白质加工, 转译后(Protein Processing, Post-Translational)

DOI 10.1074/jbc.M114.614578

PMID 25505265

发布时间 2024-02-10

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The Journal of biological chemistry

The Journal of biological chemistry

2015年290卷6期

3293-307页

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