PU.1 opposes IL-7-dependent proliferation of developing B cells with involvement of the direct target gene bruton tyrosine kinase.

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作者： Darah A,Christie ^[1] ; Li S,Xu ^[1] ; Shereen A,Turkistany ^[1] ; Lauren A,Solomon ^[1] ; Stephen K H,Li ^[1] ; Edmund,Yim ^[1] ; Ian,Welch ^[2] ; Gillian I,Bell ^[3] ; David A,Hess ^[4] ; Rodney P,DeKoter ^[5]

作者单位： Centre for Human Immunology, Department of Microbiology and Immunology, University of Western Ontario, London, Ontario N6A 5C1, Canada; ^[1] Department of Animal Care and Veterinary Services, University of Western Ontario, London, Ontario N6A 5C1, Canada; ^[2] Robarts Research Institute, University of Western Ontario, London, Ontario N6A 5C1, Canada; Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario N6A 5C1, Canada; and. ^[3] Robarts Research Institute, University of Western Ontario, London, Ontario N6A 5C1, Canada; Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario N6A 5C1, Canada; and Division of Genetics and Development, Children's Health Research Institute, Lawson Research Institute, London, Ontario N6C 2R5, Canada. ^[4] Centre for Human Immunology, Department of Microbiology and Immunology, University of Western Ontario, London, Ontario N6A 5C1, Canada; Division of Genetics and Development, Children's Health Research Institute, Lawson Research Institute, London, Ontario N6C 2R5, Canada rdekoter@uwo.ca. ^[5]