换一批Early developability screen of therapeutic antibody candidates using Taylor dispersion analysis and UV area imaging detection.
第一作者：
Alexandra,Lavoisier
第一单位：
a Biologics Center ; Novartis Institutes for Biomedical Research ; Basel , Switzerland.
作者：
关键词
APSDulbecco phosphate buffered saline; hIgGTaylor dispersionTaylor dispersion analysis; CEUV array imaging detectionactive pixel sensor; TDAcapillary electrophoresis; DLScoefficient of variationdevelopability assessmentdynamic light scattering; dPBSfragment antigen-binding; IDhuman immunoglobulin G; mIgGhydrodynamic radiushydrodynamic radius; S-DASinternal diameter; ODmillipascal seconds; Rhmonoclonal antibodiesmonoclonal antibody; Fabmouse immunoglobulin G; mAboutside diameter; mPa.sscaling factor; STDselection developability assessment; SEC-LCsize-exclusion liquid chromatography; SFstandard deviation; CVviscosity
医学主题词
抗体, 单克隆(Antibodies, Monoclonal);HEK293细胞(HEK293 Cells);人类(Humans);流体动力学(Hydrodynamics);紫外线(Ultraviolet Rays)
DOI
10.4161/19420862.2014.985544
PMID
25514497
发布时间
2018-11-13
- 浏览101
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
