Targeting arterial wall sulfated glycosaminoglycans in rabbit atherosclerosis with a mouse/human chimeric antibody.
第一作者:
Yosdel,Soto
第一单位:
a Research and Development Direction, Center of Molecular Immunology , Havana , Cuba.
作者:
关键词
ID/g, percentage of injected dose per gram of tissueAt-R, Atherosclerotic rabbitsCS, chondroitin sulfateCSPG, chondroitin sulfate proteoglycansDS, dermatan sulfateELISA, enzyme-linked immunoadsorbent assayGAG, glycosaminoglycanLDL, low density lipoproteinNZW rabbits, New Zealand White rabbitsNon At-R, Non atherosclerotic rabbitPG, proteoglycansatherosclerosisglycosaminoglycansimagingmAb, monoclonal antibodymonoclonal antibodiestechnetium-99m
主题词
动物(Animals);抗体, 单克隆(Antibodies, Monoclonal);主动脉(Aorta);动脉粥样硬化(Atherosclerosis);复方合剂(Drug Combinations);荧光抗体技术(Fluorescent Antibody Technique);葡糖氨基聚糖类(Glycosaminoglycans);人类(Humans);男(雄)性(Male);小鼠(Mice);有机锝化合物(Organotechnetium Compounds);磷脂类(Phospholipids);兔(Rabbits);放射免疫显像(Radioimmunodetection);重组融合蛋白质类(Recombinant Fusion Proteins);山梨醇(Sorbitol);硫酸盐类(Sulfates);锝(Technetium);时间因素(Time Factors);组织分布(Tissue Distribution)
DOI
10.4161/mabs.29970
PMID
25517318
发布时间
2021-01-02
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