Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved.-论文-万方医学网

第一作者： Kevin,Wiehe

第一单位： Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA. Electronic address: kevin.wiehe@dm.duke.edu.

作者： Kevin,Wiehe ^[1] ; David,Easterhoff ^[2] ; Kan,Luo ^[2] ; Nathan I,Nicely ^[2] ; Todd,Bradley ^[2] ; Frederick H,Jaeger ^[2] ; S Moses,Dennison ^[2] ; Ruijun,Zhang ^[2] ; Krissey E,Lloyd ^[2] ; Christina,Stolarchuk ^[2] ; Robert,Parks ^[2] ; Laura L,Sutherland ^[2] ; Richard M,Scearce ^[2] ; Lynn,Morris ^[3] ; Jaranit,Kaewkungwal ^[4] ; Sorachai,Nitayaphan ^[5] ; Punnee,Pitisuttithum ^[4] ; Supachai,Rerks-Ngarm ^[6] ; Faruk,Sinangil ^[7] ; Sanjay,Phogat ^[8] ; Nelson L,Michael ^[9] ; Jerome H,Kim ^[9] ; Garnett,Kelsoe ^[2] ; David C,Montefiori ^[2] ; Georgia D,Tomaras ^[2] ; Mattia,Bonsignori ^[2] ; Sampa,Santra ^[10] ; Thomas B,Kepler ^[11] ; S Munir,Alam ^[2] ; M Anthony,Moody ^[2] ; Hua-Xin,Liao ^[2] ; Barton F,Haynes ^[12]

作者单位： Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA. Electronic address: kevin.wiehe@dm.duke.edu. ^[1] Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA. ^[2] National Institute for Communicable Diseases, Johannesburg 2131, SA and the Centre for the AIDS Programme of Research in South Africa (CAPRISA). ^[3] Department of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand. ^[4] Armed Forces Research Institute of Medical Sciences (AFRIMS), Bangkok 10400, Thailand. ^[5] Department of Disease Control, Ministry of Public Health, Nonthaburi 11000, Thailand. ^[6] Sanofi Pasteur, Inc., Swiftwater, PA 18370, USA. ^[7] Global Solutions for Infectious Diseases, South San Francisco, CA 94080, USA. ^[8] US Military Research Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA. ^[9] Beth Israel Deaconess Medical Center, Harvard University School of Medicine, Boston, MA 02215, USA. ^[10] Department of Microbiology, Boston University, Boston, MA 02118, USA. ^[11] Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA. Electronic address: barton.haynes@dm.duke.edu. ^[12]

医学主题词艾滋病疫苗(AIDS Vaccines);氨基酸序列(Amino Acid Sequence);动物(Animals);抗体, 病毒(Antibodies, Viral);抗体亲和力(Antibody Affinity);B-淋巴细胞(B-Lymphocytes);细胞, 培养的(Cells, Cultured);临床试验(主题)(Clinical Trials as Topic);保守序列(Conserved Sequence);表位作图(Epitope Mapping);表位, B淋巴细胞(Epitopes, B-Lymphocyte);HIV包膜蛋白质gp120(HIV Envelope Protein gp120);HIV感染(HIV Infections);HIV-1(HIV-1);人类(Humans);免疫球蛋白轻链(Immunoglobulin Light Chains);猕猴(Macaca mulatta);分子序列数据(Molecular Sequence Data);突变(Mutation);种系发生(Phylogeny);蛋白质结合(Protein Binding);蛋白质工程(Protein Engineering)

DOI 10.1016/j.immuni.2014.11.014

PMID 25526306

发布时间 2019-01-08

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Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved.

Immunity

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Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved.

Immunity

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同项目论文

Immunity

相关期刊

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