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Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants.

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第一作者： Hassan S,Dashti

第一单位： From the Nutrition and Genomics Laboratory (HSD, CES, KR, and JMO), Nutritional Epidemiology Laboratory (PFJ), and Cardiovascular Nutrition Laboratory (SL-F), Jean Mayer U.S. Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA; the Department of Mathematics, Computer Science, and Cooperative Engineering, University of St. Thomas, Houston, TX (JLF); the Translational Gerontology Branch (TT and LF) and Laboratory of Neurogenetics (DGH), National Institute on Aging, Baltimore, MD; the Divisions of Sleep and Circadian Disorders (BEC, DJG, RS, and FAJLS) and Cardiovascular Medicine and Channing Division of Network Medicine (DM), Brigham and Women's Hospital, Boston, MA; the Divisions of Sleep Medicine (BEC, DJG, and FAJLS) and Cardiovascular Medicine and Channing Division of Network Medicine (DM), Harvard Medical School, Boston, MA; the Sleep Disorders Center, VA Boston Healthcare System, Boston, MA (DJG); the Department of Nutrition, Harvard School of Public Health, Boston, MA (AH and DM); the Center for Human Genetic Research and Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA (RS); the Departments of Mental Health and Substance Abuse Services (LK and TP) and Chronic Disease Prevention (M-MP, MP, ASH, VS, and JGE) and National Institute for Health and Welfare (THL), Helsinki, Finland; the Cardiovascular Health Research Unit (TMB, RNL, and BMP), Departments of Medicine (TMB, RNL, BMP, and SAG), Biostatistics (TMB and WCJ), and Epidemiology and Health Services (BMP), Computational Medicine Core (SAG), Center for Lung Biology (SAG), and University of Washington Medicine Sleep Center (SAG), University of Washington, Seattle, WA; The Novo Nordisk Foundation Center for Basic Metabolic Research (AJ, NG, TH, and OP) and Department of Clinical Medicine (AL), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; the USDA

作者： Hassan S,Dashti ^[1] ; Jack L,Follis ^[1] ; Caren E,Smith ^[1] ; Toshiko,Tanaka ^[1] ; Brian E,Cade ^[1] ; Daniel J,Gottlieb ^[1] ; Adela,Hruby ^[1] ; Paul F,Jacques ^[1] ; Stefania,Lamon-Fava ^[1] ; Kris,Richardson ^[1] ; Richa,Saxena ^[1] ; Frank A J L,Scheer ^[1] ; Leena,Kovanen ^[1] ; Traci M,Bartz ^[1] ; Mia-Maria,Perälä ^[1] ; Anna,Jonsson ^[1] ; Alexis C,Frazier-Wood ^[1] ; Ioanna-Panagiota,Kalafati ^[1] ; Vera,Mikkilä ^[1] ; Timo,Partonen ^[1] ; Rozenn N,Lemaitre ^[1] ; Jari,Lahti ^[1] ; Dena G,Hernandez ^[1] ; Ulla,Toft ^[1] ; W Craig,Johnson ^[1] ; Stavroula,Kanoni ^[1] ; Olli T,Raitakari ^[1] ; Markus,Perola ^[1] ; Bruce M,Psaty ^[1] ; Luigi,Ferrucci ^[1] ; Niels,Grarup ^[1] ; Heather M,Highland ^[1] ; Loukianos,Rallidis ^[2] ; Mika,Kähönen ; Aki S,Havulinna ; David S,Siscovick ; Katri,Räikkönen ; Torben,Jørgensen ; Jerome I,Rotter ; Panos,Deloukas ; Jorma S A,Viikari ; Dariush,Mozaffarian ; Allan,Linneberg ; Ilkka,Seppälä ; Torben,Hansen ; Veikko,Salomaa ; Sina A,Gharib ; Johan G,Eriksson ; Stefania,Bandinelli ; Oluf,Pedersen ; Stephen S,Rich ; George,Dedoussis ; Terho,Lehtimäki ; José M,Ordovás

作者单位： From the Nutrition and Genomics Laboratory (HSD, CES, KR, and JMO), Nutritional Epidemiology Laboratory (PFJ), and Cardiovascular Nutrition Laboratory (SL-F), Jean Mayer U.S. Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA; the Department of Mathematics, Computer Science, and Cooperative Engineering, University of St. Thomas, Houston, TX (JLF); the Translational Gerontology Branch (TT and LF) and Laboratory of Neurogenetics (DGH), National Institute on Aging, Baltimore, MD; the Divisions of Sleep and Circadian Disorders (BEC, DJG, RS, and FAJLS) and Cardiovascular Medicine and Channing Division of Network Medicine (DM), Brigham and Women's Hospital, Boston, MA; the Divisions of Sleep Medicine (BEC, DJG, and FAJLS) and Cardiovascular Medicine and Channing Division of Network Medicine (DM), Harvard Medical School, Boston, MA; the Sleep Disorders Center, VA Boston Healthcare System, Boston, MA (DJG); the Department of Nutrition, Harvard School of Public Health, Boston, MA (AH and DM); the Center for Human Genetic Research and Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA (RS); the Departments of Mental Health and Substance Abuse Services (LK and TP) and Chronic Disease Prevention (M-MP, MP, ASH, VS, and JGE) and National Institute for Health and Welfare (THL), Helsinki, Finland; the Cardiovascular Health Research Unit (TMB, RNL, and BMP), Departments of Medicine (TMB, RNL, BMP, and SAG), Biostatistics (TMB and WCJ), and Epidemiology and Health Services (BMP), Computational Medicine Core (SAG), Center for Lung Biology (SAG), and University of Washington Medicine Sleep Center (SAG), University of Washington, Seattle, WA; The Novo Nordisk Foundation Center for Basic Metabolic Research (AJ, NG, TH, and OP) and Department of Clinical Medicine (AL), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; the USDA ^[1] From the Nutrition and Genomics Laboratory (HSD, CES, KR, and JMO), Nutritional Epidemiology Laboratory (PFJ), and Cardiovascular Nutrition Laboratory (SL-F), Jean Mayer U.S. Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA; the Department of Mathematics, Computer Science, and Cooperative Engineering, University of St. Thomas, Houston, TX (JLF); the Translational Gerontology Branch (TT and LF) and Laboratory of Neurogenetics (DGH), National Institute on Aging, Baltimore, MD; the Divisions of Sleep and Circadian Disorders (BEC, DJG, RS, and FAJLS) and Cardiovascular Medicine and Channing Division of Network Medicine (DM), Brigham and Women's Hospital, Boston, MA; the Divisions of Sleep Medicine (BEC, DJG, and FAJLS) and Cardiovascular Medicine and Channing Division of Network Medicine (DM), Harvard Medical School, Boston, MA; the Sleep Disorders Center, VA Boston Healthcare System, Boston, MA (DJG); the Department of Nutrition, Harvard School of Public Health, Boston, MA (AH and DM); the Center for Human Genetic Research and Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA (RS); the Departments of Mental Health and Substance Abuse Services (LK and TP) and Chronic Disease Prevention (M-MP, MP, ASH, VS, and JGE) and National Institute for Health and Welfare (THL), Helsinki, Finland; the Cardiovascular Health Research Unit (TMB, RNL, and BMP), Departments ^[2]

关键词 CLOCK circadian rhythm dietary intake gene-environment interaction sleep duration