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作者：
Li-San,Wang [1]
;
Adam C,Naj [2]
;
Robert R,Graham [3]
;
Paul K,Crane [4]
;
Brian W,Kunkle [5]
;
Carlos,Cruchaga [6]
;
Josue D Gonzalez,Murcia [7]
;
Lisa,Cannon-Albright [8]
;
Clinton T,Baldwin [9]
;
Henrik,Zetterberg [10]
;
Kaj,Blennow [11]
;
Walter A,Kukull [12]
;
Kelley M,Faber [13]
;
Nicole,Schupf [14]
;
Maria C,Norton [15]
;
JoAnn T,Tschanz [16]
;
Ronald G,Munger [17]
;
Christopher D,Corcoran [18]
;
Ekaterina,Rogaeva [19]
;
Alzheimer's Disease Genetics Consortium [1]
;
Chiao-Feng,Lin [1]
;
Beth A,Dombroski [1]
;
Laura B,Cantwell [1]
;
Amanda,Partch [1]
;
Otto,Valladares [20]
;
Hakon,Hakonarson [21]
;
Peter,St George-Hyslop [22]
;
Robert C,Green [6]
;
Alison M,Goate [13]
;
Tatiana M,Foroud [23]
;
Regina M,Carney [24]
;
Eric B,Larson [3]
;
Timothy W,Behrens [7]
;
John S K,Kauwe [25]
;
Jonathan L,Haines [26]
;
Lindsay A,Farrer [27]
;
Margaret A,Pericak-Vance [28]
;
Richard,Mayeux [1]
;
Gerard D,Schellenberg ;
National Institute on Aging-Late-Onset Alzheimer’s Disease (NIA-LOAD) Family Study ;
Marilyn S,Albert ;
Roger L,Albin ;
Liana G,Apostolova ;
Steven E,Arnold ;
Robert,Barber ;
Michael,Barmada ;
Lisa L,Barnes ;
Thomas G,Beach ;
James T,Becker ;
Gary W,Beecham ;
Duane,Beekly ;
David A,Bennett ;
Eileen H,Bigio ;
Thomas D,Bird ;
Deborah,Blacker ;
Bradley F,Boeve ;
James D,Bowen ;
Adam,Boxer ;
James R,Burke ;
Joseph D,Buxbaum ;
Nigel J,Cairns ;
Chuanhai,Cao ;
Chris S,Carlson ;
Steven L,Carroll ;
Helena C,Chui ;
David G,Clark ;
David H,Cribbs ;
Elizabeth A,Crocco ;
Charles,DeCarli ;
Steven T,DeKosky ;
F Yesim,Demirci ;
Malcolm,Dick ;
Dennis W,Dickson ;
Ranjan,Duara ;
Nilufer,Ertekin-Taner ;
Kenneth B,Fallon ;
Martin R,Farlow ;
Steven,Ferris ;
Matthew P,Frosch ;
Douglas R,Galasko ;
Mary,Ganguli ;
Marla,Gearing ;
Daniel H,Geschwind ;
Bernardino,Ghetti ;
John R,Gilbert ;
Jonathan D,Glass ;
Neill R,Graff-Radford ;
John H,Growdon ;
Ronald L,Hamilton ;
Kara L,Hamilton-Nelson ;
Lindy E,Harrell ;
Elizabeth,Head ;
Lawrence S,Honig ;
Christine M,Hulette ;
Bradley T,Hyman ;
Gail P,Jarvik ;
Gregory A,Jicha ;
Lee-Way,Jin ;
Gyungah,Jun ;
Gyungah,Jun ;
M Ilyas,Kamboh ;
Anna,Karydas ;
Jeffrey A,Kaye ;
Ronald,Kim ;
Edward H,Koo ;
Neil W,Kowall ;
Joel H,Kramer ;
Frank M,LaFerla ;
James J,Lah ;
James B,Leverenz ;
Allan I,Levey ;
Gei,Li ;
Andrew P,Lieberman ;
Oscar L,Lopez ;
Kathryn L,Lunetta ;
Constantine G,Lyketsos ;
Wendy J,Mack ;
Daniel C,Marson ;
Eden R,Martin ;
Frank,Martiniuk ;
Deborah C,Mash ;
Eliezer,Masliah ;
Wayne C,McCormick ;
Susan M,McCurry ;
Andrew N,McDavid ;
Ann C,McKee ;
W Marsel,Mesulam ;
Bruce L,Miller ;
Carol A,Miller ;
Joshua W,Miller ;
Thomas J,Montine ;
John C,Morris ;
Jill R,Murrell ;
John M,Olichney ;
Joseph E,Parisi ;
William,Perry ;
Elaine,Peskind ;
Ronald C,Petersen ;
Aimee,Pierce ;
Wayne W,Poon ;
Huntington,Potter ;
Joseph F,Quinn ;
Ashok,Raj ;
Murray,Raskind ;
Eric M,Reiman ;
Barry,Reisberg ;
Christiane,Reitz ;
John M,Ringman ;
Erik D,Roberson ;
Howard J,Rosen ;
Roger N,Rosenberg ;
Mary,Sano ;
Andrew J,Saykin ;
Julie A,Schneider ;
Lon S,Schneider ;
William W,Seeley ;
Amanda G,Smith ;
Joshua A,Sonnen ;
Salvatore,Spina ;
Robert A,Stern ;
Rudolph E,Tanzi ;
Tricia A,Thornton-Wells ;
John Q,Trojanowski ;
Juan C,Troncoso ;
Debby W,Tsuang ;
Vivianna M,Van Deerlin ;
Linda J,Van Eldik ;
Badri N,Vardarajan ;
Harry V,Vinters ;
Jean Paul,Vonsattel ;
Sandra,Weintraub ;
Kathleen A,Welsh-Bohmer ;
Jennifer,Williamson ;
Sarah,Wishnek ;
Randall L,Woltjer ;
Clinton B,Wright ;
Steven G,Younkin ;
Chang-En,Yu ;
Lei,Yu
作者单位：
Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia.
[1]
Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia.
[2]
Department of Human Genetics, Genentech Inc, South San Francisco, California.
[3]
Department of Medicine, University of Washington, Seattle.
[4]
John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida.
[5]
Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri7Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St Louis, Missouri.
[6]
Department of Biology, Brigham Young University, Provo, Utah.
[7]
Division of Genetic Epidemiology, Department of Medicine, University of Utah School of Medicine, Salt Lake City10George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah.
[8]
Biomedical Genetics, Department of Medicine, Boston University, Boston, Massachusetts.
[9]
Institute of Neurology, University College London, London, England13Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska Uni.
[10]
Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, Mölndal, Sweden.
[11]
Department of Epidemiology, University of Washington, Seattle.
[12]
Department of Medical and Molecular Genetics, Indiana University, Indianapolis.
[13]
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York17Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York18Gertrude H. Sergievsky Center, Columbia.
[14]
Department of Family, Consumer, and Human Development, Utah State University, Logan20Department of Psychology, Utah State University, Logan.
[15]
Department of Psychology, Utah State University, Logan.
[16]
Department of Nutrition, Dietetics, and Food Sciences, Utah State University, Logan.
[17]
Department of Mathematics and Statistics, Utah State University, Logan.
[18]
Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada.
[19]
Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
[20]
Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada25Cambridge Institute for Medical Research, Department of Clinical Neurosciences, University of Cambridge, Cambridge, England.
[21]
Division of Genetics, Department of Medicine and Partners Center for Personalized Genetic Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts.
[22]
Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, Florida.
[23]
Department of Medicine, University of Washington, Seattle28Group Health Research Institute, Seattle, Washington.
[24]
Center for Human Genetics and Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee.
[25]
Department of Biology, Brigham Young University, Provo, Utah30Department of Biostatistics, Boston University, Boston, Massachusetts31Department of Ophthalmology, Boston University, Boston, Massachusetts32Department of Neurology, Boston University, Boston.
[26]
John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida34Dr John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida.
[27]
Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York18Gertrude H. Sergievsky Center, Columbia University, New York, New York35Department of Neurology, Columbia University, New York, New York.
[28]
主题词
老年人(Aged);老年人, 80以上(Aged, 80 and over);阿尔茨海默病(Alzheimer Disease);淀粉样β蛋白前体(Amyloid beta-Protein Precursor);病例对照研究(Case-Control Studies);女(雌)性(Female);基因型(Genotype);人类(Humans);男(雄)性(Male);系谱(Pedigree);瑞典(Sweden);美国(United States)
DOI
10.1001/jamaneurol.2014.2157
PMID
25531812
发布时间
2022-05-18
- 浏览6
JAMA neurology
JAMA neurology
2015年72卷2期
209-16页
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