The neddylation-cullin 2-RBX1 E3 ligase axis targets tumor suppressor RhoB for degradation in liver cancer.
第一作者:
Junfeng,Xu
第一单位:
From the ‡Cancer Institute, Fudan University Shanghai Cancer Center, §Department of Oncology and ¶Institutes of Biomedical Sciences, Shanghai Medical College, and.
作者:
主题词
载体蛋白质类(Carrier Proteins);细胞系, 肿瘤(Cell Line, Tumor);CULLIN蛋白质类(Cullin Proteins);HCT116细胞(HCT116 Cells);Hep G2细胞(Hep G2 Cells);人类(Humans);肝肿瘤(Liver Neoplasms);蛋白质组学(Proteomics);信号传导(Signal Transduction);泛素类(Ubiquitins);ρB GTP结合蛋白质(rhoB GTP-Binding Protein)
DOI
10.1074/mcp.M114.045211
PMID
25540389
发布时间
2022-03-21
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