Prenatal metformin exposure in a maternal high fat diet mouse model alters the transcriptome and modifies the metabolic responses of the offspring.
第一作者:
Henriikka,Salomäki
第一单位:
Department of Pharmacology, Drug Development and Therapeutics, Institute of Biomedicine, University of Turku, FI-20014 Turku, Finland; Drug Research Doctoral Programme (DRDP), University of Turku, Turku, Finland.
作者:
主题词
脂细胞(Adipocytes);脂肪因子类(Adipokines);脂肪组织, 白色(Adipose Tissue, White);动物(Animals);血糖(Blood Glucose);体重(Body Weight);细胞大小(Cell Size);女(雌)性(Female);胎儿(Fetus);葡糖耐量试验(Glucose Tolerance Test);脂类(Lipids);肝(Liver);男(雄)性(Male);二甲双胍(Metformin);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);妊娠(Pregnancy);产前暴露迟发效应(Prenatal Exposure Delayed Effects)
DOI
10.1371/journal.pone.0115778
PMID
25541979
发布时间
2022-03-17
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PloS one
e115778页
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