Serotonin-2C antagonism augments the effect of citalopram on serotonin and dopamine levels in the ventral tegmental area and nucleus accumbens.

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作者： Anniek K D,Visser ^[1] ; Jelle,Kleijn ^[2] ; Martijn H J R,van Faassen ^[3] ; Eliyahu,Dremencov ^[4] ; Gunnar,Flik ^[5] ; Ido P,Kema ^[3] ; Johan A,Den Boer ^[6] ; Aren,van Waarde ^[7] ; Rudi A J O,Dierckx ^[1] ; Fokko J,Bosker ^[8]

作者单位： Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. ^[1] Department of Biomonitoring and Sensoring, University of Groningen, Antonius Deasinglaan 1, 9713 AV Groningen, The Netherlands. ^[2] Laboratory Medicine, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. ^[3] Institutes of Molecular Physiology and Genetics and Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia. ^[4] Brains On-Line, P.O. Box 4030, 9701 EA Groningen, The Netherlands. ^[5] Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands; Director Scientific Affairs, PRA Health Sciences, Stationsweg 163, P.O. Box 200, 9470 AE Zuidlaren, The Netherlands. ^[6] Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. Electronic address: a.van.waarde@umcg.nl. ^[7] University Center of Psychiatry, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. ^[8]

关键词 5-HT2C receptor Dopamine Microdialysis SSRI augmentation Serotonin