首页> International journal of clinical and experimental pathology> Gastrointestinal stromal tumors with exon 8 c-kit gene mutation might occur at extragastric sites and have metastasis-prone nature.

Gastrointestinal stromal tumors with exon 8 c-kit gene mutation might occur at extragastric sites and have metastasis-prone nature.

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第一作者： Takashi,Ito

第一单位： Department of Surgical Pathology, Hyogo College of Medicine Hyogo, Japan ; Department of Pathology, Sanda Municipal Hospital Hyogo, Japan.

作者： Takashi,Ito ^[1] ; Masahiro,Yamamura ^[2] ; Toshihiro,Hirai ^[3] ; Takashi,Ishikawa ^[4] ; Tatsuo,Kanda ^[5] ; Takuya,Nakai ^[6] ; Mizuka,Ohkouchi ^[7] ; Yuka,Hashikura ^[7] ; Koji,Isozaki ^[7] ; Seiichi,Hirota ^[7]

作者单位： Department of Surgical Pathology, Hyogo College of Medicine Hyogo, Japan ; Department of Pathology, Sanda Municipal Hospital Hyogo, Japan. ^[1] Department of Clinical Oncology, Kawasaki Medical School Okayama, Japan. ^[2] Department of Surgery, Division of Gastroenterology, Kawasaki Medical School Okayama, Japan. ^[3] Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences Niigata, Japan. ^[4] Department of Surgery, Sanjo General Hospital Niigata, Japan. ^[5] Department of Surgery, Faculty of Medicine, Kinki University Osaka, Japan. ^[6] Department of Surgical Pathology, Hyogo College of Medicine Hyogo, Japan. ^[7]

关键词 GIST c-kit gene exon 8 gain-of-function mutation imatinib sunitinib