In vitro and in vivo conditional sensitization of hepatocellular carcinoma cells to TNF-induced apoptosis by taxol.
第一作者:
V G,Minero
第一单位:
a Department of Clinical and Biological Sciences ; Experimental Medicine and Clinical Pathology Unit; University of Turin ; Turin , Italy.
作者:
关键词
COL, colchicineDAPI, 4,6-diamidino-2-phenylindole dihydrochlorideHCC, hepatocellular carcinomaNOC, nocodazoleSOCS3SOCS3, suppressor of cytokine signaling 3STAT3, signal transducer and activator of tanscription 3TAXTAX, taxol (paclitaxel)TNFTNF, tumor necrosis factor-αTNF-R1, TNF-receptor 1TRAIL, tumor necrosis factor-related apoptosis-inducing ligandapoptosishepatocellular carcinoma
主题词
动物(Animals);抗肿瘤药, 植物(Antineoplastic Agents, Phytogenic);CASP8和FADD样细胞凋亡调节蛋白质(CASP8 and FADD-Like Apoptosis Regulating Protein);癌, 肝细胞(Carcinoma, Hepatocellular);半胱氨酸天冬氨酸蛋白酶(Caspases);细胞形状(Cell Shape);细胞存活(Cell Survival);抗药性, 肿瘤(Drug Resistance, Neoplasm);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);酶激活(Enzyme Activation);Hep G2细胞(Hep G2 Cells);人类(Humans);肝肿瘤(Liver Neoplasms);男(雄)性(Male);小鼠, 近交BALB C(Mice, Inbred BALB C);肿瘤移植(Neoplasm Transplantation);紫杉酚(Paclitaxel);受体, 肿瘤坏死因子, Ⅰ型(Receptors, Tumor Necrosis Factor, Type I);STAT3转录因子(STAT3 Transcription Factor);细胞因子信号转导蛋白抑制因子(Suppressor of Cytokine Signaling Proteins);肿瘤坏死因子α(Tumor Necrosis Factor-alpha)
DOI
10.1080/15384101.2014.1000695
PMID
25564714
发布时间
2020-09-30
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Cell cycle (Georgetown, Tex.)
1090-102页
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