首页> The Journal of neuroscience : the official journal of the Society for Neuroscience> Disturbed neuronal ER-Golgi sorting of unassembled glycine receptors suggests altered subcellular processing is a cause of human hyperekplexia.

Disturbed neuronal ER-Golgi sorting of unassembled glycine receptors suggests altered subcellular processing is a cause of human hyperekplexia.

导出 OA

翻译打印收藏纠错

第一作者： Natascha,Schaefer

第一单位： Institute for Clinical Neurobiology, Julius-Maximilians-University of Würzburg, 97078 Würzburg, Germany.

作者： Natascha,Schaefer ^[1] ; Christoph J,Kluck ^[2] ; Kerry L,Price ^[3] ; Heike,Meiselbach ^[4] ; Nadine,Vornberger ^[1] ; Stephan,Schwarzinger ^[5] ; Stephanie,Hartmann ^[2] ; Georg,Langlhofer ^[1] ; Solveig,Schulz ^[6] ; Nadja,Schlegel ^[7] ; Knut,Brockmann ^[8] ; Bryan,Lynch ^[9] ; Cord-Michael,Becker ^[2] ; Sarah C R,Lummis ^[3] ; Carmen,Villmann ^[10]

作者单位： Institute for Clinical Neurobiology, Julius-Maximilians-University of Würzburg, 97078 Würzburg, Germany. ^[1] Institute of Biochemistry, Department of Biochemistry and Molecular Medicine, Friedrich-Alexander-University Erlangen-Nürnberg, 91054 Erlangen, Germany. ^[2] Department of Biochemistry, University of Cambridge, Cambridge CB2 1QW, United Kingdom. ^[3] Institute of Biochemistry, Bioinformatics Department, Friedrich-Alexander-University Erlangen-Nürnberg, 91054 Erlangen, Germany. ^[4] Research Center for Bio-Macromolecules and Department of Biopolymers, University Bayreuth, 95447 Bayreuth, Germany. ^[5] Center of Human Genetics and. ^[6] Department of Neuropediatrics, Jena University Hospital, 07743 Jena, Germany. ^[7] Interdisciplinary Pediatric Center for Children with Developmental Disabilities and Severe Chronic Disorders, University Medical Center, Georg August University, 37075 Göttingen, Germany, and. ^[8] Temple Street Children's University Hospital, Dublin, Dublin1, Ireland. ^[9] Institute for Clinical Neurobiology, Julius-Maximilians-University of Würzburg, 97078 Würzburg, Germany, Villmann_C@ukw.de. ^[10]

关键词 assembly biogenesis glycine receptor human hyperekplexia rescue of function subcompartimentalization