Impact of repeated measures of joint space width on the sample size calculation: An application to hip osteoarthritis.

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作者： Paul,Ornetti ^[1] ; Laure,Gossec ^[2] ; Davy,Laroche ^[3] ; Christophe,Combescure ^[4] ; Maxime,Dougados ^[5] ; Jean-Francis,Maillefert ^[6]

作者单位： Rheumatology department, Medicine Faculty, Dijon University Hospital, 21000 Dijon, France; Inserm U1093, Burgundy University, 21000 Dijon, France; Paris-Descartes University, Medicine Faculty, UPRES-EA 4058, Cochin Hospital, Rheumatology B Department, 75014 Paris, France. Electronic address: paul.ornetti@chu-dijon.fr. ^[1] CIC-P Inserm 1432, Plateforme d'Investigation Technologique, Dijon University Hospital, Dijon, France; Rheumatology department, Pitié-Salpétrière Hospital, AP-HP, 75013 Paris, France. ^[2] CIC-P Inserm 1432, Plateforme d'Investigation Technologique, Dijon University Hospital, 21000 Dijon, France. ^[3] Division of clinical epidemiology, Geneva University Hospital and University of Geneva, 1211 Geneva, Switzerland. ^[4] Paris-Descartes University, Medicine Faculty, UPRES-EA 4058, Cochin Hospital, Rheumatology B Department, 75014 Paris, France. ^[5] Rheumatology department, Medicine Faculty, Dijon University Hospital, 21000 Dijon, France; Inserm U1093, Burgundy University, 21000 Dijon, France. ^[6]

关键词 Hip Joint space Osteoarthritis Randomized clinical trial Sample size Smallest detectable difference