Characterization of a bispecific FLT3 X CD3 antibody in an improved, recombinant format for the treatment of leukemia.

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作者： Michael,Durben ^[1] ; Dominik,Schmiedel ^[2] ; Martin,Hofmann ^[1] ; Fabian,Vogt ^[3] ; Tina,Nübling ^[4] ; Elwira,Pyz ^[2] ; Hans-Jörg,Bühring ^[4] ; Hans-Georg,Rammensee ^[3] ; Helmut R,Salih ^[5] ; Ludger,Große-Hovest ^[1] ; Gundram,Jung ^[3]

作者单位： 1] Department of Immunology, Eberhard Karls Universität Tübingen, Tübingen, Germany [2] Present address: Synimmune GmbH, Auf der Morgenstelle 15, Tübingen, Germany. ^[1] Department of Immunology, Eberhard Karls Universität Tübingen, Tübingen, Germany. ^[2] 1] Department of Immunology, Eberhard Karls Universität Tübingen, Tübingen, Germany [2] German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany. ^[3] Department of Internal Medicine 2, Eberhard Karls Universität Tübingen, Tübingen, Germany. ^[4] 1] Department of Internal Medicine 2, Eberhard Karls Universität Tübingen, Tübingen, Germany [2] Clinical Collaboration Unit Translational Immunology, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany. ^[5]

主题词动物(Animals);抗体, 双特异性(Antibodies, Bispecific);白血病, 实验性(Leukemia, Experimental);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);fms样酪氨酸激酶3(fms-Like Tyrosine Kinase 3)

DOI 10.1038/mt.2015.2

PMID 25578618

发布时间 2018-11-13

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