Synthesis and pharmacological evaluation of N-benzyl substituted 4-bromo-2,5-dimethoxyphenethylamines as 5-HT2A/2C partial agonists.

导出 LinkOut

翻译打印收藏纠错

作者： Martin,Hansen ^[1] ; Stine Engesgaard,Jacobsen ^[2] ; Shane,Plunkett ^[2] ; Gudrun Eckhard,Liebscher ^[2] ; John D,McCorvy ^[3] ; Hans,Bräuner-Osborne ^[2] ; Jesper Langgaard,Kristensen ^[4]

作者单位： Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 København Ø, Denmark; Center for Integrated Molecular Brain Imaging (CIMBI), Rigshospitalet and University of Copenhagen, Blegdamsvej 9, 2100 Copenhagen, Denmark. ^[1] Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 København Ø, Denmark. ^[2] Pharmacology Department, School of Medicine, University of North Carolina at Chapel Hill, 120 Mason Farm Road, 4009 Genetic Medicine Bldg, Campus Box 7365, Chapel Hill, NC 27599-7365, United States. ^[3] Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 København Ø, Denmark; Center for Integrated Molecular Brain Imaging (CIMBI), Rigshospitalet and University of Copenhagen, Blegdamsvej 9, 2100 Copenhagen, Denmark. Electronic address: jesper.kristensen@sund.ku.dk. ^[4]

关键词 5-HT(2A) agonists N-Benzyl phenethylamines Selectivity Serotonin Structure activity relations