Tumor necrosis factor (TNF)-α-induced repression of GKAP42 protein levels through cGMP-dependent kinase (cGK)-Iα causes insulin resistance in 3T3-L1 adipocytes.-论文-万方医学网

作者： Yasutoshi,Ando ^[1] ; Yusuke,Shinozawa ^[1] ; Yumi,Iijima ^[1] ; Bu-Chin,Yu ^[1] ; Meri,Sone ^[1] ; Yuko,Ooi ^[1] ; Yusuke,Watanaka ^[1] ; Kazuhiro,Chida ^[1] ; Fumihiko,Hakuno ^[2] ; Shin-Ichiro,Takahashi ^[1]

作者单位： From the Departments of Animal Sciences and Applied Biological Chemistry, Graduate School of Agriculture and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan. ^[1] From the Departments of Animal Sciences and Applied Biological Chemistry, Graduate School of Agriculture and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan ahakuno@mail.ecc.u-tokyo.ac.jp. ^[2]

主题词 3T3-L1细胞(3T3-L1 Cells);衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);脂细胞(Adipocytes);动物(Animals);CHO细胞(CHO Cells);仓鼠亚科(Cricetinae);仓鼠属(Cricetulus);抗药性(Drug Resistance);葡萄糖转运体4型(Glucose Transporter Type 4);HEK293细胞(HEK293 Cells);人类(Humans);降血糖药(Hypoglycemic Agents);免疫印迹法(Immunoblotting);胰岛素(Insulin);胰岛素受体底物蛋白质类(Insulin Receptor Substrate Proteins);小鼠(Mice);显微镜检查, 共焦(Microscopy, Confocal);磷酰化(Phosphorylation);蛋白质结合(Protein Binding);蛋白质转运(Protein Transport);RNA干扰(RNA Interference);肿瘤坏死因子α(Tumor Necrosis Factor-alpha);双杂交系统技术(Two-Hybrid System Techniques);酪氨酸(Tyrosine)

DOI 10.1074/jbc.M114.624759

PMID 25586176

发布时间 2021-02-05

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Tumor necrosis factor (TNF)-α-induced repression of GKAP42 protein levels through cGMP-dependent kinase (cGK)-Iα causes insulin resistance in 3T3-L1 adipocytes.

The Journal of biological chemistry

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The Journal of biological chemistry

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Tumor necrosis factor (TNF)-α-induced repression of GKAP42 protein levels through cGMP-dependent kinase (cGK)-Iα causes insulin resistance in 3T3-L1 adipocytes.

The Journal of biological chemistry

相似文献

The Journal of biological chemistry

相关期刊

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