Determination and pharmacokinetic study of pirfenidone in rat plasma by UPLC-MS/MS.

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第一作者： Wei,Sun

第一单位： The Second Affiliated Hospital & Yuying Children' s Hospital of Wenzhou Medical University, Wenzhou 325027, China.

作者： Wei,Sun ^[1] ; Zhe-li,Jiang ^[2] ; Lei,Zhou ^[1] ; Rui-min,Chen ^[1] ; Zhe,Wang ^[1] ; Wan-shu,Li ^[3] ; Shuo-min,Jiang ^[1] ; Guo-xin,Hu ^[2] ; Rui-jie,Chen ^[4]

作者单位： The Second Affiliated Hospital & Yuying Children' s Hospital of Wenzhou Medical University, Wenzhou 325027, China. ^[1] School of Pharmacy, Wenzhou Medical University, Wenzhou 325035, China. ^[2] Ningbo Municipal Hospital of TCM, Ningbo 315010, China. ^[3] The Second Affiliated Hospital & Yuying Children' s Hospital of Wenzhou Medical University, Wenzhou 325027, China. Electronic address: crj@wzhealth.com. ^[4]

关键词 Pharmacokinetics Pirfenidone Rat plasma UPLC–MS/MS

主题词动物(Animals);色谱法, 高压液相(Chromatography, High Pressure Liquid);药物稳定性(Drug Stability);检测限(Limit of Detection);男(雄)性(Male);吡啶酮类(Pyridones);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);结果可重复性(Reproducibility of Results);串联质谱法(Tandem Mass Spectrometry)

DOI 10.1016/j.jchromb.2014.12.027

PMID 25596380

发布时间 2015-01-26

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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

2015年981-982卷

14-8页

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Determination and pharmacokinetic study of pirfenidone in rat plasma by UPLC-MS/MS.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

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Determination and pharmacokinetic study of pirfenidone in rat plasma by UPLC-MS/MS.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

相似文献

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

相关期刊

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