Facile syntheses of functionalized toll-like receptor 7 agonists.

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第一作者： Babatope,Akinbobuyi

第一单位： Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798, USA.

作者： Babatope,Akinbobuyi ^[1] ; Matthew R,Byrd ^[1] ; Charles A,Chang ^[2] ; Mysa,Nguyen ^[1] ; Zacharie J,Seifert ^[1] ; Anne-Laure,Flamar ^[3] ; Gerard,Zurawski ^[4] ; Katherine C,Upchurch ^[2] ; SangKon,Oh ^[4] ; Stephen H,Dempsey ^[5] ; Thomas J,Enke ^[5] ; John,Le ^[5] ; Hunter J,Winstead ^[5] ; José R,Boquín ^[5] ; Robert R,Kane ^[6]

作者单位： Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798, USA. ^[1] Institute of Biomedical Studies, Baylor University, One Bear Place #97224, Waco, TX 76798, USA. ^[2] Baylor Institute for Immunology Research, Baylor Research Institute, 3434 Live Oak Street, Dallas, TX 75204, USA. ^[3] Institute of Biomedical Studies, Baylor University, One Bear Place #97224, Waco, TX 76798, USA ; Baylor Institute for Immunology Research, Baylor Research Institute, 3434 Live Oak Street, Dallas, TX 75204, USA. ^[4] Department of Chemistry, Augustana College, 639 38 Street, Rock Island, IL 61201, USA. ^[5] Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798, USA ; Institute of Biomedical Studies, Baylor University, One Bear Place #97224, Waco, TX 76798, USA ; Baylor Institute for Immunology Research, Baylor Research Institute, 3434 Live Oak Street, Dallas, TX 75204, USA. ^[6]

关键词 Adenine derivatives Immune activation Toll-like receptor Vaccines

DOI 10.1016/j.tetlet.2014.11.126

PMID 25601818

发布时间 2019-11-20

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