Reversal of hemochromatosis by apotransferrin in non-transfused and transfused Hbbth3/+ (heterozygous B1/B2 globin gene deletion) mice.-论文-万方医学网

第一作者： Monique P,Gelderman

第一单位： Laboratory of Biochemistry and Vascular Biology, Center of Biologics Evaluation and Research (CBER), FDA, Silver Spring, MD, USA.

作者： Monique P,Gelderman ^[1] ; Jin Hyen,Baek ^[2] ; Ayla,Yalamanoglu ^[3] ; Michele,Puglia ^[4] ; Florence,Vallelian ^[5] ; Bo,Burla ^[5] ; Jaroslav,Vostal ^[1] ; Dominik J,Schaer ^[6] ; Paul W,Buehler ^[7]

作者单位： Laboratory of Biochemistry and Vascular Biology, Center of Biologics Evaluation and Research (CBER), FDA, Silver Spring, MD, USA. ^[1] Laboratory of Cellular Hematology, Center of Biologics Evaluation and Research (CBER), FDA, Silver Spring, MD, USA. ^[2] Laboratory of Cellular Hematology, Center of Biologics Evaluation and Research (CBER), FDA, Silver Spring, MD, USA Division of Internal Medicine, University of Zurich, Switzerland. ^[3] Functional Genomics Center Zurich, Swiss Federal Institute of Technology Zurich / University of Zurich, Switzerland Division of Internal Medicine, University of Zurich, Switzerland. ^[4] Division of Internal Medicine, University of Zurich, Switzerland. ^[5] Division of Internal Medicine, University of Zurich, Switzerland Center of Evolutionary Medicine, University of Zurich, Switzerland. ^[6] Laboratory of Cellular Hematology, Center of Biologics Evaluation and Research (CBER), FDA, Silver Spring, MD, USA paul.buehler@fda.hhs.gov dominik.schaer@usz.ch. ^[7]

医学主题词动物(Animals);脱辅蛋白质类(Apoproteins);输血(Blood Transfusion);阳离子转运蛋白质类(Cation Transport Proteins);细胞因子类(Cytokines);疾病模型, 动物(Disease Models, Animal);红细胞指数(Erythrocyte Indices);女(雌)性(Female);基因缺失(Gene Deletion);基因表达(Gene Expression);血色素沉着症(Hemochromatosis);铁(Iron);肝(Liver);男(雄)性(Male);小鼠(Mice);肌蛋白质类(Muscle Proteins);心肌(Myocardium);脾(Spleen);脾大(Splenomegaly);转铁蛋白(Transferrin);β珠蛋白类(beta-Globins)

DOI 10.3324/haematol.2014.117325

PMID 25616571

发布时间 2025-01-03

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Reversal of hemochromatosis by apotransferrin in non-transfused and transfused Hbbth3/+ (heterozygous B1/B2 globin gene deletion) mice.

Haematologica

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Reversal of hemochromatosis by apotransferrin in non-transfused and transfused Hbbth3/+ (heterozygous B1/B2 globin gene deletion) mice.

Haematologica

相似文献

同项目论文

Haematologica

相关期刊

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