换一批Epigenetic heterogeneity of developmentally important genes in human sperm: implications for assisted reproduction outcome.
第一作者：
Juliane,Kuhtz
第一单位：
a Institute of Human Genetics ; Julius Maximilians University ; Würzburg , Germany.
作者：
关键词
ART outcomeART, assisted reproductive technologyDBS, deep bisulfite sequencingGTL2ICSIICSI, intracytoplasmatic sperm injectionIMSIIMSI, intracytoplasmic morphologically selected sperm injectionLD, limiting dilutionOAT, oligoasthenoteratozoospermiaPCR, polymerase chain reactionSNP, single nucleotide polymorphismdeep bisulfite sequencingepigenetic heterogeneitysperm DNA methylation
医学主题词
弱精子症(Asthenozoospermia);CpG岛(CpG Islands);DNA甲基化(DNA Methylation);后成说, 遗传(Epigenesis, Genetic);基因组印迹(Genomic Imprinting);高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);同源盒结构域蛋白质类(Homeodomain Proteins);人类(Humans);Kruppel样转录因子类(Kruppel-Like Transcription Factors);男(雄)性(Male);八聚体转录因子3(Octamer Transcription Factor-3);钾通道, 电压门控(Potassium Channels, Voltage-Gated);RNA结合蛋白质类(RNA-Binding Proteins);参考值(Reference Values);单细胞分析(Single-Cell Analysis);精子发生(Spermatogenesis);精子(Spermatozoa);亚硫酸盐类(Sulfites)
DOI
10.4161/15592294.2014.988063
PMID
25625849
发布时间
2021-01-18
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Epigenetics
1648-58页
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