Robust passive and active efflux of cellular cholesterol to a designer functional mimic of high density lipoprotein.

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作者： Andrea J,Luthi ^[1] ; Nicholas N,Lyssenko ^[2] ; Duyen,Quach ^[2] ; Kaylin M,McMahon ^[3] ; John S,Millar ^[4] ; Kasey C,Vickers ^[5] ; Daniel J,Rader ^[4] ; Michael C,Phillips ^[2] ; Chad A,Mirkin ^[6] ; C Shad,Thaxton ^[7]

作者单位： Department of Chemistry Northwestern University, Evanston, IL 60208. ^[1] Lipid Research Group, Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104 Division of Translational Medicine and Human Genetics, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104. ^[2] Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611 Walter S. and Lucienne Driskill Graduate Training Program in Life Sciences, Northwestern University, Chicago, IL 60611 Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611. ^[3] Division of Translational Medicine and Human Genetics, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104. ^[4] Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232. ^[5] Department of Chemistry Northwestern University, Evanston, IL 60208 International Institute for Nanotechnology, Northwestern University, Evanston, IL 60208. ^[6] Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 International Institute for Nanotechnology, Northwestern University, Evanston, IL 60208 Simpson Querrey Institute for BioNanotechnology and Medicine, Northwestern University, Chicago, IL 60611. ^[7]

关键词 ATP-binding cassette transporter A1 ATP-binding cassette transporter G1 atherosclerosis cholesterol efflux macrophages scavenger receptor class B type I