Learning from our failures in blood-brain permeability: what can be done for new drug discovery?

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作者： Sylvain,Martel ^[1]

作者单位： NanoRobotics Laboratory, Polytechnique Montréal, Department of Computer and Software Engineering, and Institute of Biomedical Engineering , Montréal (Québec) , Canada sylvain.martel@polymtl.ca. ^[1]

关键词 blood–brain barrier carrier-mediated transport hyperthermia nanotechnology navigable agents receptor-mediated transport

主题词动物(Animals);生物转运(Biological Transport);血脑屏障(Blood-Brain Barrier);脑(Brain);脑疾病(Brain Diseases);药物释放系统(Drug Delivery Systems);药物设计(Drug Design);药物发现(Drug Discovery);人类(Humans);通透性(Permeability);药用制剂(Pharmaceutical Preparations)

DOI 10.1517/17460441.2015.1009443

PMID 25658294

发布时间 2015-02-23

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Expert opinion on drug discovery

2015年10卷3期

207-11页

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Learning from our failures in blood-brain permeability: what can be done for new drug discovery?

Expert opinion on drug discovery

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Learning from our failures in blood-brain permeability: what can be done for new drug discovery?

Expert opinion on drug discovery

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Expert opinion on drug discovery

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