Development of surface modified biodegradable polymeric nanoparticles to deliver GSE24.2 peptide to cells: a promising approach for the treatment of defective telomerase disorders.
第一作者:
Susana P,Egusquiaguirre
第一单位:
NanoBioCel Group, Laboratory of Pharmaceutics, School of Pharmacy, University of the Basque Country (UPV/EHU), Vitoria-Gasteiz, Spain; Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Vitoria-Gasteiz, Spain.
作者:
医学主题词
动物(Animals);生物相容性材料(Biocompatible Materials);生物转运(Biological Transport);细胞周期蛋白质类(Cell Cycle Proteins);细胞系(Cell Line);细胞存活(Cell Survival);细胞穿透性肽类(Cell-Penetrating Peptides);细胞, 培养的(Cells, Cultured);化学现象(Chemical Phenomena);迟效制剂(Delayed-Action Preparations);药物调剂(Drug Compounding);药物释放系统(Drug Delivery Systems);药物稳定性(Drug Stability);先天性角化不良(Dyskeratosis Congenita);酶再激活剂(Enzyme Reactivators);人类(Humans);乳酸(Lactic Acid);小鼠(Mice);纳米粒子(Nanoparticles);核蛋白质类(Nuclear Proteins);肽碎片(Peptide Fragments);聚胺类(Polyamines);聚乙烯二醇类(Polyethylene Glycols);羟基乳酸聚合物910(Polyglactin 910);聚乙醇酸(Polyglycolic Acid);蛋白质稳定性(Protein Stability);重组蛋白质类(Recombinant Proteins);末端转移酶端粒(Telomerase)
DOI
10.1016/j.ejpb.2015.01.028
PMID
25660910
发布时间
2020-12-09
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