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首页> Neurobiology of disease> Enhanced histamine H2 excitation of striatal cholinergic interneurons in L-DOPA-induced dyskinesia.

Enhanced histamine H2 excitation of striatal cholinergic interneurons in L-DOPA-induced dyskinesia.

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作者： Sean Austin O,Lim ^[1] ; Rong,Xia ^[2] ; Yunmin,Ding ^[3] ; Lisa,Won ^[2] ; William J,Ray ^[4] ; Stephen A,Hitchcock ^[4] ; Daniel S,McGehee ^[5] ; Un Jung,Kang ^[6]

作者单位： Committee on Neurobiology, University of Chicago, Chicago, IL 60637, USA. ^[1] Department of Neurology, University of Chicago, Chicago, IL 60637, USA. ^[2] Department of Neurology, University of Chicago, Chicago, IL 60637, USA; Department of Neurology, Columbia University, New York, NY 10032, USA. ^[3] Envoy Therapeutics, Inc., Jupiter, FL 33458, USA. ^[4] Committee on Neurobiology, University of Chicago, Chicago, IL 60637, USA; Department of Anesthesia & Critical Care, University of Chicago, Chicago, IL 60637, USA. Electronic address: dmcgehee@uchicago.edu. ^[5] Committee on Neurobiology, University of Chicago, Chicago, IL 60637, USA; Department of Neurology, University of Chicago, Chicago, IL 60637, USA; Department of Neurology, Columbia University, New York, NY 10032, USA. Electronic address: ujk2101@cumc.columbia.edu. ^[6]

关键词 6-OHDA lesion Aphakia Cholinergic interneuron Famotidine Histamine Parkinson's disease Striatum l-DOPA induced dyskinesia

主题词动作电位(Action Potentials);动物(Animals);纹状体(Corpus Striatum);双环维林(Dicyclomine);疾病模型, 动物(Disease Models, Animal);运动障碍, 药物性(Dyskinesia, Drug-Induced);法莫替丁(Famotidine);组胺H2拮抗剂(Histamine H2 Antagonists);中间神经元(Interneurons);左旋多巴(Levodopa);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);帕金森病(Parkinson Disease);受体, 组胺H2(Receptors, Histamine H2)

DOI 10.1016/j.nbd.2015.01.003

PMID 25661301

发布时间 2022-10-17

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Neurobiology of disease

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