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首页> Biochimica et biophysica acta> New proline-rich oligopeptides from the venom of African adders: Insights into the hypotensive effect of the venoms.

New proline-rich oligopeptides from the venom of African adders: Insights into the hypotensive effect of the venoms.

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作者： Roberto T,Kodama ^[1] ; Daniela,Cajado-Carvalho ^[1] ; Alexandre K,Kuniyoshi ^[1] ; Eduardo S,Kitano ^[2] ; Alexandre K,Tashima ^[3] ; Barbara F,Barna ^[4] ; Ana Carolina,Takakura ^[5] ; Solange M T,Serrano ^[2] ; Wilmar,Dias-Da-Silva ^[1] ; Denise V,Tambourgi ^[1] ; Fernanda V,Portaro ^[6]

作者单位： Immunochemistry Laboratory, Butantan Institute, São Paulo, SP, Brazil. ^[1] Special Laboratory of Applied Toxinology/Center of Toxins, Immune-Response and Cell Signaling (CeTICS), Butantan Institute, São Paulo, SP, Brazil. ^[2] Department of Biochemistry, Federal University of São Paulo, São Paulo, Brazil. ^[3] Department of Physiology and Biophysics, University of São Paulo, São Paulo, Brazil. ^[4] Department of Pharmacology, University of São Paulo, São Paulo, Brazil. ^[5] Immunochemistry Laboratory, Butantan Institute, São Paulo, SP, Brazil. Electronic address: fernanda.portaro@butantan.gov.br. ^[6]

关键词 Angiotensin-converting enzyme (ACE)Bitis Bradykinin-potentiating peptide (BPP)Hypotension Proline-rich oligopeptide (PRO)Venom

主题词血管紧张素转换酶抑制药(Angiotensin-Converting Enzyme Inhibitors);动物(Animals);色谱法, 高压液相(Chromatography, High Pressure Liquid);荧光共振能量转移(Fluorescence Resonance Energy Transfer);心率(Heart Rate);低血压(Hypotension);男(雄)性(Male);寡肽类(Oligopeptides);脯氨酸(Proline);大鼠, Wistar(Rats, Wistar);肾素-血管紧张素系统(Renin-Angiotensin System);心动过速(Tachycardia);串联质谱法(Tandem Mass Spectrometry);蝰蛇毒液类(Viper Venoms)

DOI 10.1016/j.bbagen.2015.02.005

PMID 25688758

发布时间 2022-03-30

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Biochimica et biophysica acta

Biochimica et biophysica acta

2015年1850卷6期

1180-7页

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