Substrate stress relaxation regulates cell spreading.

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作者： Ovijit,Chaudhuri ^[1] ; Luo,Gu ^[2] ; Max,Darnell ^[2] ; Darinka,Klumpers ^[3] ; Sidi A,Bencherif ^[2] ; James C,Weaver ^[4] ; Nathaniel,Huebsch ^[5] ; David J,Mooney ^[2]

作者单位： 1] School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA [2] Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, Massachusetts 02138, USA [3] Department of Mechanical Engineering, Stanford University, Stanford, California 94305, USA. ^[1] 1] School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA [2] Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, Massachusetts 02138, USA. ^[2] 1] School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA [2] Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, Massachusetts 02138, USA [3] Department of Orthopedic Surgery, Research Institute MOVE, VU University Medical Center, Amsterdam, De Boelelaan 1117, 1081 HV, The Netherlands. ^[3] Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, Massachusetts 02138, USA. ^[4] 1] School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA [2] Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA. ^[5]

主题词 3T3细胞(3T3 Cells);藻酸盐(Alginates);动物(Animals);细胞黏附(Cell Adhesion);细胞培养技术(Cell Culture Techniques);细胞系, 肿瘤(Cell Line, Tumor);细胞形状(Cell Shape);细胞外基质(Extracellular Matrix);葡糖醛酸(Glucuronic Acid);己糖醛酸类(Hexuronic Acids);人类(Humans);水凝胶类(Hydrogels);动力传导, 细胞(Mechanotransduction, Cellular);小鼠(Mice);模型, 生物学(Models, Biological);应力, 物理(Stress, Mechanical);黏弹性物质(Viscoelastic Substances)

DOI 10.1038/ncomms7365

PMID 25695512

发布时间 2024-06-10

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Nature communications

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Substrate stress relaxation regulates cell spreading.

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Substrate stress relaxation regulates cell spreading.

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