换一批
换一批Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy.
作者：
关键词
AIM2, absent in melanoma 2ATG, autophagy relatedATPIF1, ATPase inhibitory factor 1BID, BH3 interacting domain death agonistBMDM, bone marrow-derived macrophagesBrdU, 5-bromo-2-deoxyuridineCASP, caspaseDNA detectionGFP, green fluorescent proteinIL1B, interleukin 1, βLC3B, microtubule-associated protein 1 light chain 3 βLDH, lactate dehydrogenaseLPS, lipopolysaccharideMT-CO1, mitochondrially encoded cytochrome c oxidase IMito-TEMPO, (2-(2, 2, 6, 6-tetramethylpiperidin-1-oxyl-4-ylamino)-2-oxoethyl)triphenylphosphonium chlorideNAC, N-acetylcysteineNAIP, NLR family apoptosis inhibitorNGS, normal goat serumNLR proteinsNLR, nucleotide-binding domain, leucine-rich repeat containingNLRC4, NLR family, CARD domain containing 4NLRP3, NLR family, pyrin domain containing 3PBS, phosphate-buffered salinePINK1, PTEN induced putative kinase 1Rn18s, 18S rRNAT3SS, type III secretion systemTNF, tumor necrosis factorTUBB5, tubulin, β 5 class IThree-MA, 3-methyladenineVav, vav 1 oncogeneinfectionmitophagymtDNA, mitochondrial DNAtype III secretion system
主题词
动物(Animals);凋亡调节蛋白质类(Apoptosis Regulatory Proteins);自噬(Autophagy);骨髓细胞(Bone Marrow Cells);钙结合蛋白质类(Calcium-Binding Proteins);DNA, 线粒体(DNA, Mitochondrial);DNA结合蛋白质类(DNA-Binding Proteins);减量调节(Down-Regulation);女(雌)性(Female);HEK293细胞(HEK293 Cells);人类(Humans);炎性体(Inflammasomes);巨噬细胞(Macrophages);小鼠, 近交C57BL(Mice, Inbred C57BL);线粒体(Mitochondria);蛋白质结合(Protein Binding);假单胞菌感染(Pseudomonas Infections);铜绿假单胞菌(Pseudomonas aeruginosa);活性氧(Reactive Oxygen Species)
DOI
10.4161/15548627.2014.981915
PMID
25700738
发布时间
2023-07-11
- 浏览89
Autophagy
166-82页
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