换一批Insights into the slow-onset tight-binding inhibition of Escherichia coli dihydrofolate reductase: detailed mechanistic characterization of pyrrolo [3,2-f] quinazoline-1,3-diamine and its derivatives as novel tight-binding inhibitors.
第一作者：
Bharath,Srinivasan
第一单位：
Center for the Study of Systems Biology, Georgia Institute of Technology, Atlanta, GA, USA.
作者：
医学主题词
二胺类(Diamines);酶抑制剂(Enzyme Inhibitors);大肠杆菌(Escherichia coli);蛋白质结合(Protein Binding);四氢叶酸脱氢酶(Tetrahydrofolate Dehydrogenase)
DOI
10.1111/febs.13244
PMID
25703118
发布时间
2018-11-13
- 浏览13
The FEBS journal
1922-38页
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