Hepatitis B Virus X Protein Stabilizes Cyclin D1 and Increases Cyclin D1 Nuclear Accumulation through ERK-Mediated Inactivation of GSK-3β.-论文-万方医学网

作者： Xiangmei,Chen ^[1] ; Ling,Zhang ^[2] ; Sujun,Zheng ^[3] ; Ting,Zhang ^[1] ; Meng,Li ^[1] ; Xiaolei,Zhang ^[1] ; Zhenzhen,Zeng ^[1] ; Malcolm A,McCrae ^[4] ; Jingmin,Zhao ^[5] ; Hui,Zhuang ^[1] ; Fengmin,Lu ^[6]

作者单位： Department of Microbiology and Infectious Disease Center, School of Basic Medical Science, Peking University Health Science Center, Beijing, P.R. China. ^[1] Department of Hepatobiliary Surgery, Henan Cancer Hospital, Zhengzhou, P.R. China. ^[2] Beijing YouAn hospital, Capital Medical University, Beijing, P.R. China. ^[3] The Pirbright Institute, Pirbright, Woking, United Kingdom. ^[4] Department of Pathology, Institute of Infectious Diseases, Beijing 302 Hospital, Beijing, P.R. China. ^[5] Department of Microbiology and Infectious Disease Center, School of Basic Medical Science, Peking University Health Science Center, Beijing, P.R. China. lu.fengmin@hsc.pku.edu.cn. ^[6]

主题词主动转运, 细胞核(Active Transport, Cell Nucleus);动物(Animals);癌, 肝细胞(Carcinoma, Hepatocellular);细胞核(Cell Nucleus);细胞转化, 病毒(Cell Transformation, Viral);细胞, 培养的(Cells, Cultured);细胞周期蛋白D1(Cyclin D1);疾病恶化(Disease Progression);酶激活(Enzyme Activation);细胞外信号调节MAP激酶类(Extracellular Signal-Regulated MAP Kinases);糖原合成酶激酶3(Glycogen Synthase Kinase 3);Hep G2细胞(Hep G2 Cells);人类(Humans);肝肿瘤(Liver Neoplasms);小鼠(Mice);NIH 3T3细胞(NIH 3T3 Cells);蛋白质稳定性(Protein Stability);蛋白质转运(Protein Transport);反式激活因子类(Trans-Activators);病毒调节和辅助蛋白质类(Viral Regulatory and Accessory Proteins)

DOI 10.1158/1940-6207.CAPR-14-0384

PMID 25712050

发布时间 2020-12-09

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Hepatitis B Virus X Protein Stabilizes Cyclin D1 and Increases Cyclin D1 Nuclear Accumulation through ERK-Mediated Inactivation of GSK-3β.

Cancer prevention research (Philadelphia, Pa.)

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Cancer prevention research (Philadelphia, Pa.)

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Hepatitis B Virus X Protein Stabilizes Cyclin D1 and Increases Cyclin D1 Nuclear Accumulation through ERK-Mediated Inactivation of GSK-3β.

Cancer prevention research (Philadelphia, Pa.)

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Cancer prevention research (Philadelphia, Pa.)

相关期刊

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