Evaluation of CYP2D6 enzyme activity using a 13C-dextromethorphan breath test in women receiving adjuvant tamoxifen.
第一作者:
Stephanie L,Safgren
第一单位:
Departments of aOncology bMolecular Pharmacology and Experimental Therapeutics cBiostatistics dLaboratory Medicine, Mayo Clinic, Rochester, Minnesota eDepartment of Hematology and Oncology, Mayo Clinic, Scottsdale, Arizona fCambridge Isotope Laboratories Inc. gPhysical Sciences Inc., Andover, Massachusetts, USA.
作者:
主题词
成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);抗肿瘤药, 激素(Antineoplastic Agents, Hormonal);镇咳药(Antitussive Agents);乳腺肿瘤(Breast Neoplasms);呼吸试验(Breath Tests);细胞色素P450 CYP2D6(Cytochrome P-450 CYP2D6);右美沙芬(Dextromethorphan);女(雌)性(Female);基因型(Genotype);人类(Humans);中年人(Middle Aged);多态性, 单核苷酸(Polymorphism, Single Nucleotide);他莫昔芬(Tamoxifen);治疗结果(Treatment Outcome)
DOI
10.1097/FPC.0000000000000121
PMID
25714002
发布时间
2018-11-13
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