Radioresistance in a human laryngeal squamous cell carcinoma cell line is associated with DNA methylation changes and topoisomerase II α.
作者:
关键词
5-Aza, 5-aza-2′-deoxycytidineBSA, Bovine Serum AlbuminDNMT, DNA methyltransferasesHRP, Horseradish peroxidaseHep-2, Human laryngeal squamous cell carcinomaHuman laryngeal squamous cell carcinomaMethylationPI, Propidium iodidePyrosequencingRR-Hep-2, Radioresistant Hep-2RT-PCR, Reverse Transcription-polymerase Chain ReactionRadioresistanceTOPO2ATOPO2A, Topoisomerase II α
主题词
抗原, 肿瘤(Antigens, Neoplasm);阿扎胞苷(Azacitidine);癌, 鳞状细胞(Carcinoma, Squamous Cell);细胞系, 肿瘤(Cell Line, Tumor);CpG岛(CpG Islands);DNA甲基化(DNA Methylation);DNA拓扑异构酶类, Ⅱ型(DNA Topoisomerases, Type II);DNA结合蛋白质类(DNA-Binding Proteins);后成说, 遗传(Epigenesis, Genetic);头颈部肿瘤(Head and Neck Neoplasms);人类(Humans);喉肿瘤(Laryngeal Neoplasms);启动区, 遗传(Promoter Regions, Genetic);辐射耐受性(Radiation Tolerance);转录, 遗传(Transcription, Genetic)
DOI
10.1080/15384047.2015.1017154
PMID
25719218
发布时间
2022-03-30
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Cancer biology & therapy
558-66页
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