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Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis.

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第一作者: Beatrice,Grabner
第一单位: Ludwig Boltzmann Institute for Cancer Research (LBI-CR), Vienna 1090, Austria.
作者单位: Ludwig Boltzmann Institute for Cancer Research (LBI-CR), Vienna 1090, Austria. [1] Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna 1030, Austria. [2] 1] Ludwig Boltzmann Institute for Cancer Research (LBI-CR), Vienna 1090, Austria [2] Institute of Animal Breeding and Genetics, University of Veterinary Medicine, Vienna 1210 and Medical University Vienna, Vienna 1090, Austria. [3] Institute of Pharmacology, Medical University of Vienna, Vienna 1090, Austria. [4] Institute of Cancer Research &Department of Internal Medicine I, Comprehensive Cancer Center, Medical University of Vienna, Vienna 1090, Austria. [5] Research Institute of Molecular Pathology (IMP), Dr. Bohr Gasse 7, Vienna 1030, Austria. [6] Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Novum, Huddinge 141 83, Sweden. [7] Department of Molecular Biology, Paris-Lodron University of Salzburg, Salzburg 5020, Austria. [8] Department of Internal Medicine, Karl Landsteiner University, 3430 Tulln, Austria. [9] 1] Ludwig Boltzmann Institute for Cancer Research (LBI-CR), Vienna 1090, Austria [2] Clinical Institute of Pathology, Medical University of Vienna, Vienna 1090, Austria [3] Unit of Pathology of Laboratory Animals (UPLA), University of Veterinary Medicine Vienna, 1210 Vienna, Austria. [10] Molecular Biotechnology Center (MBC), Department of Genetics, Biology and Biochemistry, University of Turin, Turin 10126, Italy. [11] 1] Ludwig Boltzmann Institute for Cancer Research (LBI-CR), Vienna 1090, Austria [2] Institute of Pharmacology, Medical University of Vienna, Vienna 1090, Austria. [12] Clinical Institute of Pathology, Medical University of Vienna, Vienna 1090, Austria. [13] Department of Laboratory Medicine, Medical University of Vienna, Vienna 1090, Austria. [14] 1] MTA TTK Lendület Cancer Biomarker Research Group, Budapest 1117, Hungary [2] 2nd Department of Pediatrics, Semmelweis University, Budapest 1094, Hungary [3] MTA-SE Pediatrics and Nephrology Research Group, Budapest 1083, Hungary. [15] Institute of Pathology, Research Unit Molecular Lung and Pleura Pathology, Medical University of Graz, Graz 8036, Austria. [16] 1] Ludwig Boltzmann Institute for Cancer Research (LBI-CR), Vienna 1090, Austria [2] Department of Physiology, Center of Physiology and Pharmacology, Comprehensive Cancer Center, Medical University of Vienna, Vienna 1090, Austria. [17]
DOI 10.1038/ncomms7285
PMID 25734337
发布时间 2025-05-29
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