换一批SOCS3 deficiency in leptin receptor-expressing cells mitigates the development of pregnancy-induced metabolic changes.
第一作者：
Thais T,Zampieri
第一单位：
Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, São Paulo, SP, 05508-000, Brazil.
作者：
关键词
ARH, arcuate nucleus of the hypothalamusDIO, diet-induced obesityDMH, dorsomedial nucleus of the hypothalamusEGWG, excessive gestational weight gainGDM, gestational diabetes mellitusGH-V, placental growth hormoneGTT, glucose tolerance testGestational diabetesHypothalamusIR, insulin receptorITT, insulin tolerance testLepR, leptin receptorLeptinLeptin resistanceObesityPKC, protein kinase CRP, retroperitonealSOCS3, suppressor of cytokine signaling-3STZ, streptozotocinSuppressor of cytokine signalingVMH, ventromedial nucleus of the hypothalamuspSTAT3, phosphorylation of the signal transducer and activator of transcription 3pSTAT3-ir, pSTAT3-immunoreactive
DOI
10.1016/j.molmet.2014.12.005
PMID
25737950
发布时间
2018-11-13
- 浏览38
Molecular metabolism
2015年4卷3期
237-45页
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