首页> Lancet (London, England)> Fluorouracil and dose-dense chemotherapy in adjuvant treatment of patients with early-stage breast cancer: an open-label, 2 × 2 factorial, randomised phase 3 trial.

Fluorouracil and dose-dense chemotherapy in adjuvant treatment of patients with early-stage breast cancer: an open-label, 2 × 2 factorial, randomised phase 3 trial.

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第一作者： Lucia,Del Mastro

第一单位： Department of Medical Oncology, IRCCS AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy. Electronic address: lucia.delmastro@hsanmartino.it.

作者： Lucia,Del Mastro ^[1] ; Sabino,De Placido ^[2] ; Paolo,Bruzzi ^[3] ; Michele,De Laurentiis ^[4] ; Corrado,Boni ^[5] ; Giovanna,Cavazzini ^[6] ; Antonio,Durando ^[7] ; Anna,Turletti ^[8] ; Cecilia,Nisticò ^[9] ; Enrichetta,Valle ^[10] ; Ornella,Garrone ^[11] ; Fabio,Puglisi ^[12] ; Filippo,Montemurro ^[13] ; Sandro,Barni ^[14] ; Andrea,Ardizzoni ^[15] ; Teresa,Gamucci ^[16] ; Giuseppe,Colantuoni ^[17] ; Mario,Giuliano ^[2] ; Adriano,Gravina ^[4] ; Paola,Papaldo ^[9] ; Claudia,Bighin ^[18] ; Giancarlo,Bisagni ^[5] ; Valeria,Forestieri ^[2] ; Francesco,Cognetti ^[9] ; Gruppo Italiano Mammella (GIM) investigators

作者单位： Department of Medical Oncology, IRCCS AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy. Electronic address: lucia.delmastro@hsanmartino.it. ^[1] Medical Oncology, Azienda Ospedaliera Universitaria Federico II, Napoli, Italy. ^[2] Epidemiology Unit, IRCCS AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy. ^[3] Medical Oncology, Istituto Nazionale Tumori-IRCCS Fondazione Pascale, Napoli, Italy. ^[4] Medical Oncology, IRCCS Arcispedale S Maria Nuova, Reggio Emilia, Italy. ^[5] Medical Oncology, Azienda Ospedaliera Carlo Poma, Mantova, Italy. ^[6] Breast Unit, Azienda Ospedaliera Universitaria Città della Saute e delle Scienze, Torino, Italy. ^[7] Medical Oncology, ASLTO1, Torino, Italy. ^[8] Department of Medical Oncology, Istituto Regina Elena per lo Studio e la Cura dei Tumori, Roma, Italy. ^[9] Medical Oncology, ASL8-Ospedale Oncologico, A Businco, Cagliari, Italy. ^[10] Department of Medical Oncology, Ospedale di Insegnamento S Croce e Carle, Cuneo, Italy. ^[11] Department of Oncology, Azienda Ospedaliera di Udine, Udine, Italy. ^[12] Investigative Clinical Oncology, Fondazione del Piemonte per l'Oncologia/Candiolo Cancer Center (IRCCS), Candiolo, Torino, Italy. ^[13] Medical Oncology, Azienda Ospedaliera, Caravaggio, Treviglio, Bergamo, Italy. ^[14] Medical Oncology, Azienda Ospedaliera Universitaria, Parma, Italy. ^[15] Medical Oncology, ASL Frosinone, Ospedale SS, Trinità, Sora, Frosinone, Italy. ^[16] Medical Oncology, Azienda Ospedaliera S Giuseppe Moscati, Avellino, Italy. ^[17] Department of Medical Oncology, IRCCS AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy. ^[18]