Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects.-论文-万方医学网

第一作者： Jasmin,Wellbrock

第一单位： Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald University Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

作者： Jasmin,Wellbrock ^[1] ; Emily,Latuske ^[1] ; Julian,Köhler ^[1] ; Katharina,Wagner ^[2] ; Hauke,Stamm ^[1] ; Eik,Vettorazzi ^[3] ; Gabi,Vohwinkel ^[1] ; Marianne,Klokow ^[1] ; Roswitha,Uibeleisen ^[2] ; Patrick,Ehm ^[4] ; Kristoffer,Riecken ^[5] ; Sonja,Loges ^[6] ; Felicitas,Thol ^[2] ; Claudia,Schubert ^[7] ; Michael,Amling ^[8] ; Manfred,Jücker ^[4] ; Carsten,Bokemeyer ^[1] ; Michael,Heuser ^[2] ; Jürgen,Krauter ^[2] ; Walter,Fiedler ^[9]

作者单位： Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald University Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. ^[1] Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany. ^[2] Department of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. ^[3] Center for Experimental Medicine, Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. ^[4] Research Department Cell and Gene Therapy, Clinic for Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. ^[5] Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald University Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. ^[6] Department of Transfusion Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. ^[7] Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. ^[8] Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald University Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. fiedler@uke.de. ^[9]

医学主题词青少年(Adolescent);成年人(Adult);动物(Animals);病例对照研究(Case-Control Studies);细胞系, 肿瘤(Cell Line, Tumor);DNA突变分析(DNA Mutational Analysis);无病生存(Disease-Free Survival);女(雌)性(Female);猬蛋白质类(Hedgehog Proteins);人类(Humans);Kaplan-Meiers评估(Kaplan-Meier Estimate);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);男(雄)性(Male);小鼠, 近交NOD(Mice, Inbred NOD);小鼠, SCID(Mice, SCID);中年人(Middle Aged);肿瘤移植(Neoplasm Transplantation);预后(Prognosis);比例危险度模型(Proportional Hazards Models);吡啶类(Pyridines);嘧啶类(Pyrimidines);受体, G-蛋白偶联(Receptors, G-Protein-Coupled);信号传导(Signal Transduction);转录因子(Transcription Factors);治疗结果(Treatment Outcome);青年人(Young Adult)

DOI 10.1158/1078-0432.CCR-14-1059

PMID 25745035

发布时间 2016-11-25

检索历史清除

Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects.

Clinical cancer research

相似文献

同项目论文

Clinical cancer research

相关期刊

参考文献：
指定格式：	NoteExpress EndNote RefWorks NoteFirst

检索历史 清除

Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects.

Clinical cancer research

相似文献

同项目论文

Clinical cancer research

相关期刊

检索历史清除