Conformational dynamics of bacterial and human cytoplasmic models of the ribosomal A-site.

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作者： Joanna,Panecka ^[1] ; Jiří,Šponer ^[2] ; Joanna,Trylska ^[3]

作者单位： Division of Biophysics, Institute of Experimental Physics, University of Warsaw, Żwirki i Wigury 93, 02-089 Warsaw, Poland; Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw, Pawińskiego 5a, 02-106 Warsaw, Poland. ^[1] CEITEC - Central European Institute of Technology, Masaryk University, Campus Bohunice, Kamenice 5, 625 00 Brno, Czech Republic; Institute of Biophysics, Academy of Sciences of the Czech Republic, Královopolská 135, 612 65 Brno, Czech Republic. Electronic address: sponer@ncbr.muni.cz. ^[2] Centre of New Technologies, University of Warsaw, Banacha 2c, 02-097 Warsaw, Poland. Electronic address: joanna@cent.uw.edu.pl. ^[3]

关键词 Aminoglycoside antibiotics Bacterial A-site Human cytoplasmic A-site Molecular dynamics simulations Ribosomal RNA

主题词结晶学, X线(Crystallography, X-Ray);大肠杆菌(Escherichia coli);人类(Humans);分子动力学模拟(Molecular Dynamics Simulation);核糖体亚单位, 小, 细菌(Ribosome Subunits, Small, Bacterial);核糖体亚单位, 小, 真核细胞(Ribosome Subunits, Small, Eukaryotic)

DOI 10.1016/j.biochi.2015.02.021

PMID 25748164

发布时间 2015-04-19

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