A simple protocol for preparation of a liposomal vesicle with encapsulated plasmid DNA that mediate high accumulation and reporter gene activity in tumor tissue.

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作者： Torben,Gjetting ^[1] ; Thomas Lars,Andresen ^[2] ; Camilla Laulund,Christensen ^[3] ; Frederik,Cramer ^[3] ; Thomas Tuxen,Poulsen ^[3] ; Hans Skovgaard,Poulsen ^[3]

作者单位： Department of Radiation Biology, section 6321, Finsen Center, Copenhagen University Hospital, Copenhagen, Denmark ; Department of Micro- and Nanotechnology, Technical University of Denmark, Kgs. Lyngby, Denmark. ^[1] Department of Micro- and Nanotechnology, Technical University of Denmark, Kgs. Lyngby, Denmark. ^[2] Department of Radiation Biology, section 6321, Finsen Center, Copenhagen University Hospital, Copenhagen, Denmark. ^[3]

关键词 Biodistribution EPR, Enhanced permeability and retention effect Gene delivery Liposome PDI, Polydispersity index PEG, Polyethylene glycol SCD, Super cytosine deaminase SCLC, Small cell lung carcinoma SPLP, Stabilized plasmid–lipid particle Stabilized plasmid–lipid particle (SPLP)Suicide gene therapy Xenograft tumor model

DOI 10.1016/j.rinphs.2011.08.001

PMID 25755981

发布时间 2020-10-01

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Results in pharma sciences

2011年1卷1期

49-56页

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A simple protocol for preparation of a liposomal vesicle with encapsulated plasmid DNA that mediate high accumulation and reporter gene activity in tumor tissue.

Results in pharma sciences

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Results in pharma sciences

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A simple protocol for preparation of a liposomal vesicle with encapsulated plasmid DNA that mediate high accumulation and reporter gene activity in tumor tissue.

Results in pharma sciences

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Results in pharma sciences

相关期刊

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