首页> International journal of nanomedicine> Oral lipid-based nanoformulation of tafenoquine enhanced bioavailability and blood stage antimalarial efficacy and led to a reduction in human red blood cell loss in mice.

Oral lipid-based nanoformulation of tafenoquine enhanced bioavailability and blood stage antimalarial efficacy and led to a reduction in human red blood cell loss in mice.

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第一作者： Paula,Melariri

第一单位： Polymers and Composites, Material Science and Manufacturing, Council for Scientific and Industrial Research, Port Elizabeth, South Africa.

作者： Paula,Melariri ^[1] ; Lonji,Kalombo ^[2] ; Patric,Nkuna ^[2] ; Admire,Dube ^[3] ; Rose,Hayeshi ^[2] ; Benhards,Ogutu ^[4] ; Liezl,Gibhard ^[5] ; Carmen,deKock ^[5] ; Peter,Smith ^[5] ; Lubbe,Wiesner ^[5] ; Hulda,Swai ^[2]

作者单位： Polymers and Composites, Material Science and Manufacturing, Council for Scientific and Industrial Research, Port Elizabeth, South Africa. ^[1] Polymer and Composites, Material Science and Manufacturing, Council for Scientific and Industrial Research, Pretoria, South Africa. ^[2] Polymer and Composites, Material Science and Manufacturing, Council for Scientific and Industrial Research, Pretoria, South Africa ; School of Pharmacy, University of the Western Cape, Bellville, South Africa. ^[3] Centre for Research in Therapeutic Sciences, Strathmore University, Nairobi, Kenya ; Centre for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya. ^[4] Division of Pharmacology, University of Cape Town Medical School, Groote Schuur Hospital, Cape Town, South Africa. ^[5]

关键词 G6PD deficiency in vivo efficacy microemulsion solubility