换一批
换一批Benzydamine N-oxygenation as an index for flavin-containing monooxygenase activity and benzydamine N-demethylation by cytochrome P450 enzymes in liver microsomes from rats, dogs, monkeys, and humans.
第一单位：
DMPK Research Laboratories, Research Division, Mitsubishi Tanabe Pharma Corporation, Toda, Saitama, Japan.
作者：
主题词
动物(Animals);消炎药(Anti-Inflammatory Agents);苄达明(Benzydamine);生物转化(Biotransformation);细胞色素P450酶系统(Cytochrome P-450 Enzyme System);狗(Dogs);人类(Humans);成束猴(Macaca fascicularis);男(雄)性(Male);甲基化(Methylation);微粒体, 肝(Microsomes, Liver);氧化还原(Oxidation-Reduction);氧合酶类(Oxygenases);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);重组蛋白质类(Recombinant Proteins);种特异性(Species Specificity)
DOI
10.1016/j.dmpk.2014.09.006
PMID
25760531
发布时间
2015-03-12
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